Synthesis of two isomeric pentasaccharides, the possible repeating unit of the beta-glucan from the micro fungus Epicoccum nigrum Ehrenb. ex Schlecht | |
Zeng, Y; Zhang, WH; Ning, J; Kong, FZ | |
刊名 | CARBOHYDRATE RESEARCH
![]() |
2002 | |
卷号 | 337期号:24页码:2383-2391 |
关键词 | Glucose Oligosaccharides Trichloroacetimidates Regio- And Stereoselective Synthesis |
DOI | 10.1016/S0008-6215(02)00317-8 |
英文摘要 | Two isomeric pentasaccharides, beta-D-Glcp-(1 --> 3)-[beta-D-Glcp-(1 --> 6)]-beta-D-Glcp-(1 --> 3)-[beta-D-Glcp-(1 --> 6)]-beta-D-Glcp (I) and beta-D-Glcp-(1 --> 6)-beta-D-Glcp-(1 --> 3)-[beta-D-Glcp-(1 --> 3)-beta-D-Glcp-(1 --> 6)]-beta-D-Glcp (II), the possible repeating unit of the beta-glucan from the micro fungus Epicoccum nigrum Ehrenb. ex Schlecht, were synthesized as their 4-methoxyphenyl glycosides in a regio- and stereoselective manner. The pentasaccharide I was obtained from 3-O-selective glycosylation of 4-methoxyphenyl 4,6-O-benzylidene-beta-D-glucopyranoside (12) with 2,3,4,6-tetra-O-benzoyl-beta-D-glucopyranosyl-(1 --> 3)-[2,3,4,6-tetra-O-benzoyl-beta-D-glucopyranosyl-(1 --> 6)]-2,4-di-O-acetyl-alpha-D-glucopyranosyl trichloroacetimidate (6) followed by acetylation, debenzylidenation, and 6-O-selective glucosylation with 2,3,4,6-tetra-O-benzoyl-beta-D-glucopyranosyl trichloroacetimidate (1), and then by deprotection. The pentasaccharide II was obtained from 3-O-selective coupling of 12 with 2,3,4,6-tetra-O-benzoyl-beta-D-glucopyranosyl-(1 --> 6)-2,4-di-O-acetyl-3-O-allyl-alpha-D-glucopyranosyl trichloroacetimidate (10) followed by acetylation, debenzylidenation, and 6-O-selective glycosylation with 2,3,4,6-tetra-O-benzoyl-beta-D-glucopyranosyl-(1 --> 3)-2,4,6-tri-O-acetyl-alpha-D-glucopyranosyl trichloroacetimidate (II), and finally by deprotection. (C) 2002 Elsevier Science Ltd. All rights reserved. |
WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
WOS记录号 | WOS:000179688900002 |
内容类型 | 期刊论文 |
源URL | [http://ir.rcees.ac.cn/handle/311016/23975] ![]() |
专题 | 生态环境研究中心_中国科学院环境生物技术重点实验室 |
推荐引用方式 GB/T 7714 | Zeng, Y,Zhang, WH,Ning, J,et al. Synthesis of two isomeric pentasaccharides, the possible repeating unit of the beta-glucan from the micro fungus Epicoccum nigrum Ehrenb. ex Schlecht[J]. CARBOHYDRATE RESEARCH,2002,337(24):2383-2391. |
APA | Zeng, Y,Zhang, WH,Ning, J,&Kong, FZ.(2002).Synthesis of two isomeric pentasaccharides, the possible repeating unit of the beta-glucan from the micro fungus Epicoccum nigrum Ehrenb. ex Schlecht.CARBOHYDRATE RESEARCH,337(24),2383-2391. |
MLA | Zeng, Y,et al."Synthesis of two isomeric pentasaccharides, the possible repeating unit of the beta-glucan from the micro fungus Epicoccum nigrum Ehrenb. ex Schlecht".CARBOHYDRATE RESEARCH 337.24(2002):2383-2391. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论