Human Exposure to Short- and Medium-Chain Chlorinated Paraffins via Mothers' Milk in Chinese Urban Population

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Human Exposure to Short- and Medium-Chain Chlorinated Paraffins via Mothers' Milk in Chinese Urban Population
	Wu, Yongning; Xia, Dan; Qiao, Lin; Gao, Lirong; Zheng, Minghui; Li, Jingguang; Zhang, Lei; Huang, Huiting; Tian, Qichang
刊名	ENVIRONMENTAL SCIENCE & TECHNOLOGY
	2017-10-17
卷号	51 期号:1 页码:608-615
英文摘要	Chlorinated paraffins (CPs) are high production volume synthetic chemicals, found ubiquitously in various environmental matrices. However, little information is available on CP contamination in mothers' milk. In this study, 1370 urban mothers' milk samples were collected from 12 Chinese provinces in 2007 and 16 provinces in 2011. CP geographical distribution and congener group profiles were studied to assess the CP levels and figure out the source of exposure in humans. Twenty-eight pooled samples were analyzed for 48 short-chain CP (SCCP) and medium-chain CP (MCCP) congener groups using the GC x GC-ECNI-HRTOFMS method. The median concentrations of SCCPs were 681 and 733 ng/g lipid in 2007 and 2011, respectively; median concentrations of MCCPs were 60.4 and 64.3 ng/g lipid in 2007 and 2011, respectively. Variations of more than 2 orders of magnitude in CP exposure levels were found between different provinces. The levels of CPs increased from 2007 to 2011, which indicates that CP production and use may be an important exposure source. This is the first global comprehensive and large-scale investigation of CPs in mothers' milk, and it lays foundations for improving our understanding of the metabolism of CPs in humans. The high CP concentrations found in Chinese mothers' milk should raise concern about potential toxic effects in both mothers and breastfeeding infants.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/39331]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Wu, Yongning,Xia, Dan,Qiao, Lin,et al. Human Exposure to Short- and Medium-Chain Chlorinated Paraffins via Mothers' Milk in Chinese Urban Population[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2017,51(1):608-615.
APA	Wu, Yongning.,Xia, Dan.,Qiao, Lin.,Gao, Lirong.,Zheng, Minghui.,...&Tian, Qichang.(2017).Human Exposure to Short- and Medium-Chain Chlorinated Paraffins via Mothers' Milk in Chinese Urban Population.ENVIRONMENTAL SCIENCE & TECHNOLOGY,51(1),608-615.
MLA	Wu, Yongning,et al."Human Exposure to Short- and Medium-Chain Chlorinated Paraffins via Mothers' Milk in Chinese Urban Population".ENVIRONMENTAL SCIENCE & TECHNOLOGY 51.1(2017):608-615.