Protein-directed synthesis of bi2s3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract | |
Zu, Yan; Yong, Yuan; Zhang, Xiao; Yu, Jie; Dong, Xinghua; Yin, Wenyan; Yan, Liang; Zhao, Feng; Gu, Zhanjun; Zhao, Yuliang | |
刊名 | Rsc advances
![]() |
2017 | |
卷号 | 7期号:28页码:17505-17513 |
ISSN号 | 2046-2069 |
DOI | 10.1039/c7ra01526g |
通讯作者 | Yan, liang() |
英文摘要 | Non-invasive imaging modalities such as computed tomography are often used for diagnosis and assessment of gastrointestinal (gi) disease status over the long-term. the physiology of the gi tract can be assessed with contrast agents. here, we present common protein (bovine serum albumin, bsa) stabilized bismuth sulfide nanoparticles with robust x-ray attenuation. under the optimal conditions, this agent can outline the anatomy of the mouse gi tract on 3d computed tomography imaging, with the real-time and non-invasive visualization of nanoparticle distribution and the gi tract. moreover, the investigation on long-term toxicity and biodistribution of these nanoparticles after oral administration indicate their overall safety. this is a promising agent for gi visualization and disease diagnosis. |
WOS关键词 | BISMUTH SULFIDE NANOPARTICLES ; LARGE-SCALE SYNTHESIS ; COMPUTED-TOMOGRAPHY ; IN-VIVO ; ASSISTED SYNTHESIS ; NANODOTS ; NANORODS ; CANCER ; DELIVERY ; THERAPY |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Multidisciplinary |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000398802000068 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2177462 |
专题 | 高能物理研究所 |
通讯作者 | Yan, Liang |
作者单位 | Chinese Acad Sci, Inst High Energy Phys, Natl Ctr Nanosci Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Zu, Yan,Yong, Yuan,Zhang, Xiao,et al. Protein-directed synthesis of bi2s3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract[J]. Rsc advances,2017,7(28):17505-17513. |
APA | Zu, Yan.,Yong, Yuan.,Zhang, Xiao.,Yu, Jie.,Dong, Xinghua.,...&Zhao, Yuliang.(2017).Protein-directed synthesis of bi2s3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract.Rsc advances,7(28),17505-17513. |
MLA | Zu, Yan,et al."Protein-directed synthesis of bi2s3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract".Rsc advances 7.28(2017):17505-17513. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论