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	An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo
	Sun, Wen1; Li, Shuyi2,3; Haupler, Bernhard4; Liu, Juan2,3; Jin, Shubin2,3; Steffen, Werner1; Schubert, Ulrich S.4; Butt, Hans-Jugen1; Liang, Xing-Jie2,3; Wu, Si1
刊名	Advanced materials
	2017-02-10
卷号	29期号:6页码:6
ISSN号	0935-9648
DOI	10.1002/adma.201603702
通讯作者	Liang, xing-jie(liangxj@nanoctr.cn) ; Wu, si(wusi@mpip-mainz.mpg.de)
英文摘要	An amphiphilic ru-containing block copolymer is used as a photoactivated polymetallodrug for anticancer phototherapy. the block copolymer self-assembles into nanoparticles, which can accumulate at tumor sites in a mouse model. red light irradiation of the block copolymer nanoparticles releases anticancer ru complexes and generates cytotoxic o-1(2), both of which can inhibit tumor growth.
WOS关键词	NEAR-INFRARED LIGHT ; MESOPOROUS SILICA NANOPARTICLES ; DRUG-DELIVERY ; UPCONVERTING NANOPARTICLES ; POLYPYRIDYL COMPLEXES ; ANTICANCER DRUG ; RU(II) COMPLEX ; UP-CONVERSION ; CANCER-CELLS ; SELECTIVITY
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000396143000011
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2176809
专题	高能物理研究所
通讯作者	Liang, Xing-Jie; Wu, Si
作者单位	1.Max Planck Inst Polymer Res, Ackermannweg 10, D-55128 Mainz, Germany 2.Chinese Acad Sci, Ctr Excellence Nanosci, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 4.Friedrich Schiller Univ Jena, Lab Organ & Macromol Chem IOMC, Jena Ctr Soft Matter JCSM, D-07743 Jena, Germany
推荐引用方式 GB/T 7714	Sun, Wen,Li, Shuyi,Haupler, Bernhard,et al. An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo[J]. Advanced materials,2017,29(6):6.
APA	Sun, Wen.,Li, Shuyi.,Haupler, Bernhard.,Liu, Juan.,Jin, Shubin.,...&Wu, Si.(2017).An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo.Advanced materials,29(6),6.
MLA	Sun, Wen,et al."An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo".Advanced materials 29.6(2017):6.

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