QQ客服 官方微博 反馈留言

	Mtor signaling in parkinson's disease
	Lan, Ai-ping; Chen, Jun; Zhao, Yuliang; Chai, Zhifang; Hu, Yi
刊名	Neuromolecular medicine
	2017-03-01
卷号	19期号:1页码:1-10
关键词	Mtor Parkinson's disease Apoptosis Alpha-synuclein Oxidative stress
ISSN号	1535-1084
DOI	10.1007/s12017-016-8417-7
通讯作者	Hu, yi(huyi@ihep.ac.cn)
英文摘要	As a key regulator of cell metabolism and survival, mechanistic target of rapamycin (mtor) emerges as a novel therapeutic target for parkinson's disease (pd). a growing body of research indicates that restoring perturbed mtor signaling in pd models can prevent neuronal cell death. nevertheless, molecular mechanisms underlying mtor-mediated effects in pd have not been fully understood yet. here, we review recent progress in characterizing the association of mtor signaling with pd risk factors and further discuss the potential roles of mtor in pd.
WOS关键词	MUTANT ALPHA-SYNUCLEIN ; CENTRAL-NERVOUS-SYSTEM ; IN-VIVO MODELS ; OXIDATIVE STRESS ; DOPAMINERGIC-NEURONS ; MAMMALIAN TARGET ; NEURODEGENERATIVE DISEASES ; HYDROGEN-PEROXIDE ; PROTEIN-KINASE ; CELL-DEATH
WOS研究方向	Neurosciences & Neurology
WOS类目	Neurosciences
语种	英语
出版者	HUMANA PRESS INC
WOS记录号	WOS:000396029500001
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2176739
专题	高能物理研究所
通讯作者	Hu, Yi
作者单位	Chinese Acad Sci, Inst High Energy Phys, Multidisciplinary Res Div, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Lan, Ai-ping,Chen, Jun,Zhao, Yuliang,et al. Mtor signaling in parkinson's disease[J]. Neuromolecular medicine,2017,19(1):1-10.
APA	Lan, Ai-ping,Chen, Jun,Zhao, Yuliang,Chai, Zhifang,&Hu, Yi.(2017).Mtor signaling in parkinson's disease.Neuromolecular medicine,19(1),1-10.
MLA	Lan, Ai-ping,et al."Mtor signaling in parkinson's disease".Neuromolecular medicine 19.1(2017):1-10.

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。