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	Investigation on the electrochemical manipulation of bio-molecules in glass nanofluidic channels
	Liu, Kun1; Hao, Ming1; Meng, Donghui2; Wan, Xujie3; Xiao, Songwen4; Sun, Songgang1; Wang, Dongyang1; Ba, Dechun1
刊名	Journal of new materials for electrochemical systems
	2015-10-01
卷号	18期号:4页码:243-249
关键词	Nanofluidics Biological chip Molecular dynamics Wet chemical etching
ISSN号	1480-2422
通讯作者	Liu, kun(kliu@mail.neu.edu.cn)
英文摘要	As the size of microfluidic channel further shrinks to nanometer, the dimension is approximate to biomolecules as well as de bye length (dl). great deals of phenomena which do not exist in the usual world will appear. the overlapping of electrical double layers (edl) in the channel and the increasing of the viscosity are such good examples. all of these phenomena lead to the fundamental research such as colloid science, transport process and micro/nanoscale hydrodynamics. it demands more advanced technique for micro/nanoscale design and fabrication as the channels downing to nanometer scale. in this work, molecular dynamics was adopted to calculate the transport of proteins and water molecules in nanofluidic channels. new methods of nanochannel fabrication were developed based on glass substrate. glass nanochips were achieved via ultraviolet lithography and wet chemical etching. the channel depth could be adjusted by controlling the etching time. finally the scanning electron microscope (sem) and surface profiler were used to characterize the shape and surface morphology of the nanochannel in detail. this study presents the feasibility of such design and fabrication methods, which gives an interesting exploration for the application of nanofluidic technology.
WOS关键词	LONG DNA-MOLECULES ; NANOCHANNELS ; SEPARATION ; DIFFUSION ; TRANSPORT ; PROTEINS ; DEVICES ; FIELD ; CHIPS
WOS研究方向	Electrochemistry ; Materials Science
WOS类目	Electrochemistry ; Materials Science, Multidisciplinary
语种	英语
出版者	ECOLE POLYTECHNIQUE MONTREAL
WOS记录号	WOS:000381248700009
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2176590
专题	高能物理研究所
通讯作者	Liu, Kun
作者单位	1.Northeastern Univ, Sch Mech Engn & Automat, 3-11 Wenhua Rd, Shenyang 110004, Peoples R China 2.Beijing Inst Spacecraft Environm Engn, Beijing 100094, Peoples R China 3.China Aviat Ind Grp Co LTD, Beijing Inst Aviat Mat, Beijing 100095, Peoples R China 4.Chinese Acad Sci, Inst High Energy Phys, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Kun,Hao, Ming,Meng, Donghui,et al. Investigation on the electrochemical manipulation of bio-molecules in glass nanofluidic channels[J]. Journal of new materials for electrochemical systems,2015,18(4):243-249.
APA	Liu, Kun.,Hao, Ming.,Meng, Donghui.,Wan, Xujie.,Xiao, Songwen.,...&Ba, Dechun.(2015).Investigation on the electrochemical manipulation of bio-molecules in glass nanofluidic channels.Journal of new materials for electrochemical systems,18(4),243-249.
MLA	Liu, Kun,et al."Investigation on the electrochemical manipulation of bio-molecules in glass nanofluidic channels".Journal of new materials for electrochemical systems 18.4(2015):243-249.

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