Micromixer based preparation of functionalized liposomes and targeting drug delivery | |
Jia, Xiangqian1,2; Wang, Weizhi1; Han, Qiuju1,2; Wang, Zihua1; Jia, Yunhong2,3; Hu, Zhiyuan1 | |
刊名 | Acs medicinal chemistry letters
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2016-04-01 | |
卷号 | 7期号:4页码:429-434 |
关键词 | Nanocarrier Her2 Antitumor Ylffvfer |
ISSN号 | 1948-5875 |
DOI | 10.1021/acsmedchemlett.6b00028 |
通讯作者 | Wang, weizhi(wangwz@nanoctr.cn) ; Jia, yunhong(jiayunhong2012@163.com) ; Hu, zhiyuan(huzy@nanoctr.cn) |
英文摘要 | We present here a specific targeting nanocarrier system by functionalization of liposomes with one new type of breast cancer targeting peptide (h6, ylffvfer) by a micromixer with high efficiency. antitumor drugs could be successfully delivered into human epidermal growth factor receptor 2 (her2) positive breast cancer cells with high efficiency in both in vivo and ex vivo models. |
WOS关键词 | BREAST-CANCER ; PEPTIDE ; TUMOR ; NANOPARTICLES ; CELLS ; THERAPY ; RELEASE |
WOS研究方向 | Pharmacology & Pharmacy |
WOS类目 | Chemistry, Medicinal |
语种 | 英语 |
出版者 | AMER CHEMICAL SOC |
WOS记录号 | WOS:000374436700018 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2176524 |
专题 | 高能物理研究所 |
通讯作者 | Wang, Weizhi; Jia, Yunhong; Hu, Zhiyuan |
作者单位 | 1.Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 2.Liaoning Med Univ, Coll Pharm, Jinzhou 121001, Liaoning, Peoples R China 3.Liaoning Med Univ, Coll Basic Sci, Jinzhou 121001, Liaoning, Peoples R China |
推荐引用方式 GB/T 7714 | Jia, Xiangqian,Wang, Weizhi,Han, Qiuju,et al. Micromixer based preparation of functionalized liposomes and targeting drug delivery[J]. Acs medicinal chemistry letters,2016,7(4):429-434. |
APA | Jia, Xiangqian,Wang, Weizhi,Han, Qiuju,Wang, Zihua,Jia, Yunhong,&Hu, Zhiyuan.(2016).Micromixer based preparation of functionalized liposomes and targeting drug delivery.Acs medicinal chemistry letters,7(4),429-434. |
MLA | Jia, Xiangqian,et al."Micromixer based preparation of functionalized liposomes and targeting drug delivery".Acs medicinal chemistry letters 7.4(2016):429-434. |
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