Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as selective Btk inhibitors with improved pharmacokinetic properties for the treatment of rheumatoid arthritis | |
Linhong He; Heying Pei; Chufeng Zhang; Mingfeng Shao; Dan Li; Mingli Tang; Taijing Wang; Xiaoxin Chen; Mingli Xiang; Lijuan Chen | |
刊名 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
2018 | |
卷号 | Vol.145页码:96-112 |
关键词 | Btk Inhibitor Selectivity Bioavailability Aqueous solubility Rheumatoid arthritis |
ISSN号 | 0223-5234 |
URL标识 | 查看原文 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/1832827 |
专题 | 四川大学 |
作者单位 | b Guangdong Zhongsheng Pharmaceutical Co., Ltd., Dongguan, Guangdong 523325, China a State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China |
推荐引用方式 GB/T 7714 | Linhong He,Heying Pei,Chufeng Zhang,et al. Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as selective Btk inhibitors with improved pharmacokinetic properties for the treatment of rheumatoid arthritis[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2018,Vol.145:96-112. |
APA | Linhong He.,Heying Pei.,Chufeng Zhang.,Mingfeng Shao.,Dan Li.,...&Lijuan Chen.(2018).Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as selective Btk inhibitors with improved pharmacokinetic properties for the treatment of rheumatoid arthritis.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,Vol.145,96-112. |
MLA | Linhong He,et al."Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as selective Btk inhibitors with improved pharmacokinetic properties for the treatment of rheumatoid arthritis".EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY Vol.145(2018):96-112. |
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