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Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer
Guo, Y.; Zhao, Y.; Wang, G.; Chen, Y.; Jiang, Y.; Ouyang, L.; Liu, B.
刊名European Journal of Medicinal Chemistry
2018
卷号Vol.143页码:402-418
关键词Anti-tumor activity Apoptosis Breast cancer Eukaryotic elongation factor 2 kinase β-phenylalanine scaffold
ISSN号0223-5234
URL标识查看原文
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/1821453
专题四川大学
作者单位1.School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China
2.a State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Collaborative Innovation Center of Biotherapy, Chengdu, China
3.Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, China
推荐引用方式
GB/T 7714
Guo, Y.,Zhao, Y.,Wang, G.,et al. Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer[J]. European Journal of Medicinal Chemistry,2018,Vol.143:402-418.
APA Guo, Y..,Zhao, Y..,Wang, G..,Chen, Y..,Jiang, Y..,...&Liu, B..(2018).Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer.European Journal of Medicinal Chemistry,Vol.143,402-418.
MLA Guo, Y.,et al."Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer".European Journal of Medicinal Chemistry Vol.143(2018):402-418.
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