Sensitive detection of free bilirubin in blood serum using beta-diketone modified europium-doped yttrium oxide nanosheets as a luminescent sensor | |
Yang, Wei; Xia, Jinfeng1; Zhou, Guohong1; Jiang, Danyu1; Li, Qiang | |
刊名 | RSC ADVANCES
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2018 | |
卷号 | 8期号:32页码:17854 |
ISSN号 | 2046-2069 |
DOI | 10.1039/c8ra02817f |
英文摘要 | Free bilirubin, when present in excess in the human body, can cause a multitude of diseases and disorders and even be fatal; hence, detecting it is of paramount importance. Herein, we report a luminescence quenching-based non-enzymatic method for the convenient, reliable, and rapid detection of free bilirubin in blood serum samples using sensing films (nanosheets/PS, nanosheets-tta/PS, and nanosheets-dbt/PS) as luminescent sensors. The luminescence intensity of the sensing films is linearly related to the free bilirubin concentration. Nanosheets-tta/PS demonstrated excellent sensing properties for the sensitive and reliable detection of free bilirubin in the range of 0.0-60.0 mu M with a correlation coefficient of 0.9915, as compared to nanosheets/PS or nanosheets-dbt/PS. The limit of detection for the determination of free bilirubin was 41 nM. This method can be used to design a sensor-based test spot as a medical detection device for the visual detection of free bilirubin. |
学科主题 | Chemistry, Multidisciplinary |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000435824500027 |
内容类型 | 期刊论文 |
源URL | [http://ir.sic.ac.cn/handle/331005/24570] ![]() |
专题 | 中国科学院上海硅酸盐研究所 |
作者单位 | 1.East China Normal Univ, Dept Chem, Shanghai 200062, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Ceram, Shanghai 200050, Peoples R China |
推荐引用方式 GB/T 7714 | Yang, Wei,Xia, Jinfeng,Zhou, Guohong,et al. Sensitive detection of free bilirubin in blood serum using beta-diketone modified europium-doped yttrium oxide nanosheets as a luminescent sensor[J]. RSC ADVANCES,2018,8(32):17854, 17859. |
APA | Yang, Wei,Xia, Jinfeng,Zhou, Guohong,Jiang, Danyu,&Li, Qiang.(2018).Sensitive detection of free bilirubin in blood serum using beta-diketone modified europium-doped yttrium oxide nanosheets as a luminescent sensor.RSC ADVANCES,8(32),17854. |
MLA | Yang, Wei,et al."Sensitive detection of free bilirubin in blood serum using beta-diketone modified europium-doped yttrium oxide nanosheets as a luminescent sensor".RSC ADVANCES 8.32(2018):17854. |
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