Quantifying intraocular scatter with near diffraction-limited double-pass point spread function

doi:10.1364/BOE.7.004595

CORC > 光电技术研究所 > 中国科学院光电技术研究所 > 自适应光学技术研究室（八室）

	Quantifying intraocular scatter with near diffraction-limited double-pass point spread function
	Zhao, Junlei 1,2,3; Xiao, Fei 1,2; Kang, Jian 1,2,3; Zhao, Haoxin 1,2; Dai, Yun 1,2; Zhang, Yudong 1,2
刊名	Biomedical Optics Express
	2016
卷号	7 期号:11 页码:4595-4604
关键词	Adaptive Optics Imaging Systems Noninvasive Medical Procedures
ISSN号	2156-7086
DOI	10.1364/BOE.7.004595
文献子类	J
英文摘要	Measurement of the double-pass (DP) point-spread function (PSF) can provide an objective and non-invasive method for estimating intraocular scatter in the human eye. The objective scatter index (OSI), which is calculated from the DP PSF images, is commonly used to quantify intraocular scatter. In this article, we simulated the effect of higher-order ocular aberrations on OSI, and the results showed that higher-order ocular aberrations had a significant influence on OSI. Then we developed an adaptive optics DP PSF measurement system (AO-DPPMS) which was capable of correcting ocular aberrations up to eighth-order radial Zernike modes over a 6.0-mm pupil. Employing this system, we obtained DP PSF images of four subjects at the fovea. OSI values with aberrations corrected up to 2nd, 5th and 8th Zernike order were calculated respectively, from the DP PSF images of the four subjects. The experimental results were consistent with the simulation, suggesting that it is necessary to compensate for the higher-order ocular aberrations for accurate intraocular scatter estimation. © 2016 Optical Society of America.
语种	英语
WOS记录号	WOS:000387557600020
资助机构	National Natural Science Foundation of China [61378064] ; National High Technology Research and Development Program of China [2015AA020511]
内容类型	期刊论文
源URL	[http://ir.ioe.ac.cn/handle/181551/8423]
专题	光电技术研究所_自适应光学技术研究室（八室）
作者单位	1.The Key Laboratory on Adaptive Optics, Chinese Academy of Sciences, Chengdu 2.610209, China 3.The Laboratory on Adaptive Optics, Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 4.610209, China 5.University of Chinese Academy of Sciences, Beijing 6.100049, China
推荐引用方式 GB/T 7714	Zhao, Junlei,Xiao, Fei,Kang, Jian,et al. Quantifying intraocular scatter with near diffraction-limited double-pass point spread function[J]. Biomedical Optics Express,2016,7(11):4595-4604.
APA	Zhao, Junlei,Xiao, Fei,Kang, Jian,Zhao, Haoxin,Dai, Yun,&Zhang, Yudong.(2016).Quantifying intraocular scatter with near diffraction-limited double-pass point spread function.Biomedical Optics Express,7(11),4595-4604.
MLA	Zhao, Junlei,et al."Quantifying intraocular scatter with near diffraction-limited double-pass point spread function".Biomedical Optics Express 7.11(2016):4595-4604.