A metal-free direct C (sp(3))-H cyanation reaction with cyanobenziodoxolones

doi:10.1039/c8ob00173a

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	A metal-free direct C (sp(3))-H cyanation reaction with cyanobenziodoxolones
	Sun, Ming-Xue 1,2; Wang, Yao-Feng 2; Xu, Bao-Hua 2; Ma, Xin-Qi 1; Zhang, Suo-Jiang 2
刊名	ORGANIC & BIOMOLECULAR CHEMISTRY
	2018-03-21
卷号	16 期号:11 页码:1971-1975
ISSN号	1477-0520
DOI	10.1039/c8ob00173a
文献子类	Article
英文摘要	A metal-free protocol of direct C(sp(3))-H cyanation with cyanobenziodoxolones functioning as both cyanating reagents and oxidants was developed. Unactivated substrates, such as alkanes, ethers and tertiary amines, were thereby transformed to the corresponding nitriles in moderate to high yields. Mechanistic studies indicated that the cyanation proceeded with two potential pathways, which is highly dependent on the substrates: (1) a free radical case for alkanes and ethers and (2) an oxidative case for tertiary amines.
WOS关键词	Beta-keto-esters ; Electrophilic Cyanation ; Alpha-cyanation ; Tertiary-amines ; Strecker Reaction ; Atom-transfer ; Ebx Reagents ; h Bonds ; Alkynylation ; Oxindoles
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:000428222500020
资助机构	National Science Foundation of China(21606238 ; Instrument Developing Project of the Chinese Academy of Sciences(YZ201521) ; CAS 100-Talent Program ; 21476240 ; U1662133)
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/24141]
专题	过程工程研究所_多相复杂系统国家重点实验室
作者单位	1.Henan Univ, Henan Engn Res Ctr Resource & Energy Recovery Was, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China 2.Chinese Acad Sci, Beijing Key Lab Ion Liquids Clean Proc, CAS Key Lab Green Proc & Engn, State Key Lab Multiphase Complex Syst,Inst Proc E, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Sun, Ming-Xue,Wang, Yao-Feng,Xu, Bao-Hua,et al. A metal-free direct C (sp(3))-H cyanation reaction with cyanobenziodoxolones[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2018,16(11):1971-1975.
APA	Sun, Ming-Xue,Wang, Yao-Feng,Xu, Bao-Hua,Ma, Xin-Qi,&Zhang, Suo-Jiang.(2018).A metal-free direct C (sp(3))-H cyanation reaction with cyanobenziodoxolones.ORGANIC & BIOMOLECULAR CHEMISTRY,16(11),1971-1975.
MLA	Sun, Ming-Xue,et al."A metal-free direct C (sp(3))-H cyanation reaction with cyanobenziodoxolones".ORGANIC & BIOMOLECULAR CHEMISTRY 16.11(2018):1971-1975.