Engineering of alkane production in cyanobacteria

CORC > 青岛生物能源与过程研究所 > 中国科学院青岛生物能源与过程研究所 > 微生物代谢工程团队

	Engineering of alkane production in cyanobacteria
	Xuefeng Lu, Weihua Wang
刊名	Cyanobacteria: Omics and Manipulation
	2017-01
页码	219-234
关键词	Alkane Production Cyanobacteria
文献子类	Chapter
英文摘要	Alkanes with defined carbon chain lengths possess higher energy density, low hygroscopicity and volatility, and compatibility with existing liquid fuel infrastructure, which are the predominant constituents of gasoline, diesel and jet fuels. Alkane biosynthesis is ubiquitous and biosynthetic pathways have been identified in cyanobacteria, photosynthetic microbes, which opens a door to engineer alkane production with high efficiency in cyanobacteria. Firstly, redirecting the carbon flux to fatty acids or acyl-acyl carrier proteins can provide larger precursor pools for further conversion to alkanes. In combination with the overexpression of alkane biosynthesis genes, alkane production can be significantly improved in engineered strains. Protein engineering for key enzymes in alkane biosynthesis pathways will further enhance the yield of alkanes. Secondly, systems biology research on cyanobacteria will increase our knowledge about the metabolism in cyanobacteria and lead to significant improvements in strain modification for alkane production. Convenient and effective molecular tools for genetic engineering of cyanobacteria will expand the ability to engineer cyanobacteria for alkane production. It is significant and promising to directly utilize solar energy and convert carbon dioxide into alkanes, drop-in biofuels, in cyanobacteria.
学科主题	生物学
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/9917]
专题	青岛生物能源与过程研究所_微生物代谢工程团队
通讯作者	Xuefeng Lu, Weihua Wang
作者单位	中国科学院青岛生物能源与过程研究所
推荐引用方式 GB/T 7714	Xuefeng Lu, Weihua Wang. Engineering of alkane production in cyanobacteria[J]. Cyanobacteria: Omics and Manipulation,2017:219-234.
APA	Xuefeng Lu, Weihua Wang.(2017).Engineering of alkane production in cyanobacteria.Cyanobacteria: Omics and Manipulation,219-234.
MLA	Xuefeng Lu, Weihua Wang."Engineering of alkane production in cyanobacteria".Cyanobacteria: Omics and Manipulation (2017):219-234.