Global Survey of Antibiotic Resistance Genes in Air

doi:10.1021/acs.est.8b02204

CORC > 地球环境研究所 > 中国科学院地球环境研究所 > 黄土与第四纪地质国家重点实验室（2010~）

	Global Survey of Antibiotic Resistance Genes in Air
	Yao, MS (Yao, Maosheng)[ 1 ]; Peccia, J (Peccia, Jordan)[ 13 ]; Chan, CK (Chan, Chak K.)[ 12 ]; Morawska, L (Morawska, Lidia)[ 11 ]; de Jesus, AL (de Jesus, Alma Lorelei)[ 11 ]; Wang, J (Wang, Jing)[ 9,10 ]; Huang, RJ (Huang, Ru-jin)[ 2 ]; Da, G (Da, Guillaume)[ 8 ]; Fan, H (Fan, Hanging)[ 7 ]; Xu, SY (Xu, Siyu)[ 6 ]
刊名	ENVIRONMENTAL SCIENCE & TECHNOLOGY
	2018-07-25
卷号	52 期号:19 页码:10975-10984
DOI	10.1021/acs.est.8b02204
文献子类	期刊论文
英文摘要	Despite its emerging significant public health concern, the presence of antibiotic resistance genes (ARGs) in urban air has not received significant attention. Here, we profiled relative abundances (as a fraction, normalized by 16S rRNA gene) of 30 ARG subtypes resistant to seven common classes of antibiotics, which are quinolones, β-lactams, macrolides, tetracyclines, sulfonamides, aminoglycosides, and vancomycins, in ambient total particulate matter (PM) using a novel protocol across 19 world cities. In addition, their longitudinal changes in PM2.5 samples in Xi’an, China as an example were also studied. Geographically, the ARGs were detected to vary by nearly 100-fold in their abundances, for example, from 0.07 (Bandung, Indonesia) to 5.6 (San Francisco, USA). The β-lactam resistance gene blaTEM was found to be most abundant, seconded by quinolone resistance gene qepA; and their corresponding relative abundances have increased by 178% and 26%, respectively, from 2004 to 2014 in Xi’an. Independent of cities, gene network analysis indicates that airborne ARGs were differentially contributed by bacterial taxa. Results here reveal that urban air is being polluted by ARGs, and different cities are challenged with varying health risks associated with airborne ARG exposure. This work highlights the threat of urban airborne transmission of ARGs and the need of redefining our current air quality standards in terms with public health.
语种	英语
内容类型	期刊论文
源URL	[http://ir.ieecas.cn/handle/361006/9659]
专题	地球环境研究所_黄土与第四纪地质国家重点实验室（2010~）
作者单位	1.Department of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520, United States 2.School of Energy and Environment, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong China; 3.International Laboratory for Air Quality and Health, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, Australia; 4.Advanced Analytical Technologies, Empa, Dübendorf 8600, Switzerland; 5.Institute of Environmental Engineering, ETH Zurich, Zurich 8093, Switzerland; 6.CERTES, Université Paris-Est Creteil, Centre d ́ ’etudes et de Recherche en Thermique, Environnement et Syste ́ mes (CERTES), ̀ Creteil 94000, France ́; 7.Department of Earth and Environmental Engineering, Columbia University, New York, New York 10027, United States; 8.Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul 08826, South Korea; 9.School of Environmental Science and Engineering, Shandong University, Jinan 250100, China; 10.School of Space and Environment, Beihang University, Beijing 100191, China;
推荐引用方式 GB/T 7714	Yao, MS ,Peccia, J ,Chan, CK ,et al. Global Survey of Antibiotic Resistance Genes in Air[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2018,52(19):10975-10984.
APA	Yao, MS .,Peccia, J .,Chan, CK .,Morawska, L .,de Jesus, AL .,...&Li, J .(2018).Global Survey of Antibiotic Resistance Genes in Air.ENVIRONMENTAL SCIENCE & TECHNOLOGY,52(19),10975-10984.
MLA	Yao, MS ,et al."Global Survey of Antibiotic Resistance Genes in Air".ENVIRONMENTAL SCIENCE & TECHNOLOGY 52.19(2018):10975-10984.