Modular Synthesis of Enantioenriched 1,1,2-Triarylethanes by an Enantioselective Arylboration and Cross-Coupling Sequence

doi:10.1021/acscatal.7b00300

	Modular Synthesis of Enantioenriched 1,1,2-Triarylethanes by an Enantioselective Arylboration and Cross-Coupling Sequence
	Liao, J (reprint author), Chinese Acad Sci, Nat Prod Res Ctr, Chengdu Inst Biol, Chengdu 610041, Peoples R China.; Wang, M; Ye, JL; Jiang, LY; Liao, Y; Yin, XM; Cao, P; Chen, B; Liao, J (reprint author), Sichuan Univ, Coll Chem Engn, Chengdu 610065, Peoples R China.; Liao, J
刊名	ACS CATALYSIS
	2017
卷号	7 期号:4 页码:2425-2429
关键词	Asymmetric Catalysis Arylboration 1 Cross-coupling 1 Modular Synthesis 2-triarylethanes
DOI	10.1021/acscatal.7b00300
产权排序	2
文献子类	Article
英文摘要	An enantioselective Cu/Pd-catalyzed borylative coupling of styrenes with aryl/alkenyl iodides was realized using a chiral sulfoxide-phosphine (SOP) ligand. Enantioenriched 1,1-diarylethyl and beta-arylhomoallylic boronates are readily prepared. A streamlined procedure merging arylboration and subsequent Pd-catalyzed Suzuki-Miyaura cross-coupling enables the modular assembly of enantioenriched 1,1,2-triarylethanes, including two medicinally important chiral small-molecule targets.
学科主题	Chemistry
语种	英语
资助机构	We thank the NSFC (Nos. 21472184, 21272226, 21572218, and 21402186) and Western-Light Foundation of CAS for financial support. J. J. Chruma (Sichuan University) provided valuable manuscript revisions. ; NSFC [21472184, 21272226, 21572218, 21402186] ; We thank the NSFC (Nos. 21472184, 21272226, 21572218, and 21402186) and Western-Light Foundation of CAS for financial support. J. J. Chruma (Sichuan University) provided valuable manuscript revisions. ; NSFC [21472184, 21272226, 21572218, 21402186] ; Western-Light Foundation of CAS ; Western-Light Foundation of CAS ; We thank the NSFC (Nos. 21472184, 21272226, 21572218, and 21402186) and Western-Light Foundation of CAS for financial support. J. J. Chruma (Sichuan University) provided valuable manuscript revisions. ; NSFC [21472184, 21272226, 21572218, 21402186] ; We thank the NSFC (Nos. 21472184, 21272226, 21572218, and 21402186) and Western-Light Foundation of CAS for financial support. J. J. Chruma (Sichuan University) provided valuable manuscript revisions. ; NSFC [21472184, 21272226, 21572218, 21402186] ; Western-Light Foundation of CAS ; Western-Light Foundation of CAS
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/29248]
专题	成都生物研究所_天然产物研究
通讯作者	Liao, J (reprint author), Chinese Acad Sci, Nat Prod Res Ctr, Chengdu Inst Biol, Chengdu 610041, Peoples R China.; Liao, J (reprint author), Sichuan Univ, Coll Chem Engn, Chengdu 610065, Peoples R China.
推荐引用方式 GB/T 7714	Liao, J ,Wang, M,Ye, JL,et al. Modular Synthesis of Enantioenriched 1,1,2-Triarylethanes by an Enantioselective Arylboration and Cross-Coupling Sequence[J]. ACS CATALYSIS,2017,7(4):2425-2429.
APA	Liao, J .,Wang, M.,Ye, JL.,Jiang, LY.,Liao, Y.,...&Liao, J.(2017).Modular Synthesis of Enantioenriched 1,1,2-Triarylethanes by an Enantioselective Arylboration and Cross-Coupling Sequence.ACS CATALYSIS,7(4),2425-2429.
MLA	Liao, J ,et al."Modular Synthesis of Enantioenriched 1,1,2-Triarylethanes by an Enantioselective Arylboration and Cross-Coupling Sequence".ACS CATALYSIS 7.4(2017):2425-2429.