Fast T1 mapping of the brain at high field using Look-Locker and.

	Fast T1 mapping of the brain at high field using Look-Locker and.
	Chung, Yiu-Cho; Zhu, Yanjie; Jia, Sen; Wu, Yin; Liu, Xin; Jiang, Ke
刊名	MAGNETIC RESONANCE IMAGING
	2017
文献子类	期刊论文
英文摘要	This study aims to develop and evaluate a new method for fast high resolution T1 mapping of the brain based on the Look-Locker technique. Single-shot turboflash sequence with high temporal acceleration is used to sample the recovery of inverted magnetization. Multi-slice interleaved acquisition within one inversion slab is used to reduce the number of inversion pulses and hence SAR. Accuracy of the proposed method was studied using simulation and validated in phantoms. It was then evaluated in healthy volunteers and stroke patients. In-vivo results were compared to values obtained by inversion recovery fast spin echo (IR-FSE) and literatures. With the new method, T1 values in phantom experiments agreed with reference values with median error <3%. For in vivo experiments, a T1 map was acquired in 335 s and the T1 maps of the whole brain were acquired in 2 min with two-slice interleaving, with a spatial resolution of 1.1 x 1.1 x 4 mm(3). The T1 values obtained were comparable to those measured with IR-FSE and those reported in literatures. These results demonstrated the feasibility of the proposed method for fast T1 mapping of the brain in both healthy volunteers and stroke patients at 3T. (C) 2016 Elsevier Inc. All rights reserved.
URL标识	查看原文
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/12046]
专题	深圳先进技术研究院_医工所
作者单位	MAGNETIC RESONANCE IMAGING
推荐引用方式 GB/T 7714	Chung, Yiu-Cho,Zhu, Yanjie,Jia, Sen,et al. Fast T1 mapping of the brain at high field using Look-Locker and.[J]. MAGNETIC RESONANCE IMAGING,2017.
APA	Chung, Yiu-Cho,Zhu, Yanjie,Jia, Sen,Wu, Yin,Liu, Xin,&Jiang, Ke.(2017).Fast T1 mapping of the brain at high field using Look-Locker and..MAGNETIC RESONANCE IMAGING.
MLA	Chung, Yiu-Cho,et al."Fast T1 mapping of the brain at high field using Look-Locker and.".MAGNETIC RESONANCE IMAGING (2017).