Highly Stretchable, Compliant, Polymeric Microelectrode Arrays for In Vivo Electrophysiological Interfacing.

	Highly Stretchable, Compliant, Polymeric Microelectrode Arrays for In Vivo Electrophysiological Interfacing.
	Qi, Dianpeng ; Liu, Zhiyuan ; Liu, Yan ; Jiang, Ying ; Leow, Wan Ru ; Pal, Mayank ; Pan, Shaowu ; Yang, Hui ; Wang, Yu ; Zhang, Xiaoqian
刊名	ADVANCED MATERIALS
	2017
文献子类	期刊论文
英文摘要	Polymeric microelectrode arrays (MEAs) are emerging as a new generation of biointegrated microelectrodes to transduce original electrochemical signals in living tissues to external electrical circuits, and vice versa. So far, the challenge of stretchable polymeric MEAs lies in the competition between high stretchability and good electrode-substrate adhesion. The larger the stretchability, the easier the delamination of electrodes from the substrate due to the mismatch in their Young's modulus. In this work, polypyrrole (PPy) electrode materials are designed, with PPy nanowires integrated on the high conductive PPy electrode arrays. By utilizing this electrode material, for the first time, stretchablepolymeric MEAs are fabricated with both high stretchability (approximate to 100%) and good electrode-substrate adhesion (1.9 MPa). In addition, low Young's modulus (450 kPa), excellent recycling stability (10 000 cycles of stretch), and high conductivity of the MEAs are also achieved. As a proof of concept, the as-prepared polymeric MEAs are successfully used for conformally recording the electrocorticograph signals from rats in normal and epileptic states, respectively. Further, these polymeric MEAs are also successful in stimulating the ischiadic nerve of the rat. This strategy provides a new perspective to the highly stretchable and mechanically stable polymeric MEAs, which are vital forcompliant neural electrodes.
URL标识	查看原文
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/11946]
专题	深圳先进技术研究院_医工所
作者单位	ADVANCED MATERIALS
推荐引用方式 GB/T 7714	Qi, Dianpeng , Liu, Zhiyuan , Liu, Yan ,et al. Highly Stretchable, Compliant, Polymeric Microelectrode Arrays for In Vivo Electrophysiological Interfacing.[J]. ADVANCED MATERIALS,2017.
APA	Qi, Dianpeng ., Liu, Zhiyuan ., Liu, Yan ., Jiang, Ying ., Leow, Wan Ru .,...& Chen, Xiaodong.(2017).Highly Stretchable, Compliant, Polymeric Microelectrode Arrays for In Vivo Electrophysiological Interfacing..ADVANCED MATERIALS.
MLA	Qi, Dianpeng ,et al."Highly Stretchable, Compliant, Polymeric Microelectrode Arrays for In Vivo Electrophysiological Interfacing.".ADVANCED MATERIALS (2017).