A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood

CORC > 长春光学精密机械与物理研究所 > 中国科学院长春光学精密机械与物理研究所 > 中科院长春光机所知识产出

	A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood
	Li, X. K.; Y. L. Zhang; B. Xue; X. G. Kong; X. M. Liu; L. P. Tu; Y. L. Chang and H. Zhang
刊名	Biosensors & Bioelectronics
	2017
卷号	92
英文摘要	Assay technologies capable of detecting biomarker concentrations in unprocessed whole blood samples are fundamental for applications in medical diagnostics. SERS nano-tags integrated fiber-optic biosensor (FOB) was realized for the first time for in situ immunoassay in whole blood. The reliability and sensitivity of this method rely, in a large extent, on the quality and properties of the SERS nano-tags. The constructed silica coated Ag SERS nano-tags as labels were used in a rapid and specific in situ FOB immune sensor to detect alpha fetoprotein (AFP) in unprocessed blood samples. Preliminary results of in vivo and in situ dynamic observation of AFP of whole blood in wistar rat highlight the power of this new method.
语种	英语
内容类型	期刊论文
源URL	[http://ir.ciomp.ac.cn/handle/181722/59024]
专题	长春光学精密机械与物理研究所_中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Li, X. K.,Y. L. Zhang,B. Xue,et al. A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood[J]. Biosensors & Bioelectronics,2017,92.
APA	Li, X. K..,Y. L. Zhang.,B. Xue.,X. G. Kong.,X. M. Liu.,...&Y. L. Chang and H. Zhang.(2017).A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood.Biosensors & Bioelectronics,92.
MLA	Li, X. K.,et al."A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood".Biosensors & Bioelectronics 92(2017).