Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study

doi:10.3866/PKU.WHXB201702201

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	Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study
	Li, HX; Liu, YC; Tang, RZ; Zhang, P; Ma, LK; Wei, CY; Wang, WF
刊名	ACTA PHYSICO-CHIMICA SINICA
	2017
卷号	33 期号:5 页码:1051-1056
关键词	Laser Flash Photolysis Difloxacin Triplet State Amino Acid
ISSN号	1000-6818
DOI	10.3866/PKU.WHXB201702201
文献子类	期刊论文
英文摘要	The reactions of triplet-state difloxacin (DFX) with various amino acids and deoxyguanylic acid in aqueous media were studied using laser flash photolysis. Tryptophan, tyrosine, cysteine, and 2'-deoxyguanosine5'-monophosphate (dGMP) were found to completely quench the triplet state of DFX in aqueous solution, the corresponding second-order rate constants being 1.97 x 10(8), 1.48 x 10(8), 1.72 x 10(8), and 6.92 x 10(7) dm(3).mol(-l).s(-1) . The quenching mechanism involves electron transfer to the photoexcited triplet state of DFX from the tryptophan, tyrosine, cysteine, and dGMP moieties, followed by fast protonation of the resulting DFX anion radical.
语种	英语
WOS记录号	WOS:000401878800027
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/27431]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
推荐引用方式 GB/T 7714	Li, HX,Liu, YC,Tang, RZ,et al. Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study[J]. ACTA PHYSICO-CHIMICA SINICA,2017,33(5):1051-1056.
APA	Li, HX.,Liu, YC.,Tang, RZ.,Zhang, P.,Ma, LK.,...&Wang, WF.(2017).Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study.ACTA PHYSICO-CHIMICA SINICA,33(5),1051-1056.
MLA	Li, HX,et al."Reactions of Triplet-State Difloxacin with Amino Acids and dGMP: A Laser Flash Photolysis Study".ACTA PHYSICO-CHIMICA SINICA 33.5(2017):1051-1056.