Special Topic: Biophysical Chemistry (1603-1730) Preface

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	Special Topic: Biophysical Chemistry (1603-1730) Preface
	Zhao, XinSheng; Wang, Shu; Huang, Fang
刊名	SCIENCE CHINA-CHEMISTRY
	2014-12-01
卷号	57 期号:12 页码:1603-1604
英文摘要	A new method to screen antibiotic combinations is demonstrated, which takes advantage of the logic-signal output of genetically engineered drug-resistant E. coli strains expressing different fluorescent proteins. Thirty-six antibiotic combinations for nine antibiotics were investigated. The operation of different logic gates can reveal the susceptibility, resistance, or synergistic effect of the antibiotic combinations in a rapid (7-8 h versus 24-28 h for typical growth-based assays), simple, quantitative and high-throughput manner. This logic-signal-based output patterns provide the basis for novel and reliable screening of antibiotic combinations and help us to both gain insight into the mechanisms of multi-drug action.
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/38604]
专题	化学研究所_其它
推荐引用方式 GB/T 7714	Zhao, XinSheng,Wang, Shu,Huang, Fang. Special Topic: Biophysical Chemistry (1603-1730) Preface[J]. SCIENCE CHINA-CHEMISTRY,2014,57(12):1603-1604.
APA	Zhao, XinSheng,Wang, Shu,&Huang, Fang.(2014).Special Topic: Biophysical Chemistry (1603-1730) Preface.SCIENCE CHINA-CHEMISTRY,57(12),1603-1604.
MLA	Zhao, XinSheng,et al."Special Topic: Biophysical Chemistry (1603-1730) Preface".SCIENCE CHINA-CHEMISTRY 57.12(2014):1603-1604.