Special Topic: Biophysical Chemistry (1603-1730) Preface | |
Zhao, XinSheng; Wang, Shu; Huang, Fang | |
刊名 | SCIENCE CHINA-CHEMISTRY
![]() |
2014-12-01 | |
卷号 | 57期号:12页码:1603-1604 |
英文摘要 | A new method to screen antibiotic combinations is demonstrated, which takes advantage of the logic-signal output of genetically engineered drug-resistant E. coli strains expressing different fluorescent proteins. Thirty-six antibiotic combinations for nine antibiotics were investigated. The operation of different logic gates can reveal the susceptibility, resistance, or synergistic effect of the antibiotic combinations in a rapid (7-8 h versus 24-28 h for typical growth-based assays), simple, quantitative and high-throughput manner. This logic-signal-based output patterns provide the basis for novel and reliable screening of antibiotic combinations and help us to both gain insight into the mechanisms of multi-drug action. |
内容类型 | 期刊论文 |
源URL | [http://ir.iccas.ac.cn/handle/121111/38604] ![]() |
专题 | 化学研究所_其它 |
推荐引用方式 GB/T 7714 | Zhao, XinSheng,Wang, Shu,Huang, Fang. Special Topic: Biophysical Chemistry (1603-1730) Preface[J]. SCIENCE CHINA-CHEMISTRY,2014,57(12):1603-1604. |
APA | Zhao, XinSheng,Wang, Shu,&Huang, Fang.(2014).Special Topic: Biophysical Chemistry (1603-1730) Preface.SCIENCE CHINA-CHEMISTRY,57(12),1603-1604. |
MLA | Zhao, XinSheng,et al."Special Topic: Biophysical Chemistry (1603-1730) Preface".SCIENCE CHINA-CHEMISTRY 57.12(2014):1603-1604. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论