Controlling Helix Sense at N- and C-Termini in Quinoline Oligoamide Foldamers by beta-Pinene-Derived Pyridyl Moieties

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	Controlling Helix Sense at N- and C-Termini in Quinoline Oligoamide Foldamers by beta-Pinene-Derived Pyridyl Moieties
	Zheng, Lu 1; Zhan, Yulin 1; Yu, Chengyuan 1; Huang, Fu 1,2; Wang, Ying 1; Jiang, Hua 1
刊名	ORGANIC LETTERS
	2017-03-17
卷号	19 期号:6 页码:1482-1485
英文摘要	A series of quinoline oligoamide foldamers bearing a beta-pinene-derived pyridyl group at the N-terminus or the C terminus were synthesized, and the efficiencies of chiral inductions have been evaluated by H-1 NMR and CD spectra. The chiral inductions were quantitative when chiral pyridyl acid was appended at the N-terminus, but were inferior when chiral pyridyl amine was appended at the C-terminus. Unexpectedly, N-oxidation on the pyridine ring at the C-terminus does not notably enhance the chiral induction efficiency in spite of the presence of three-center hydrogen bonds.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/38282]
专题	化学研究所_其它
作者单位	1.Beijing Normal Univ, Coll Chem, Key Lab Radiopharmaceut, Key Lab Theoret & Computat Photochem, Beijing 100875, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zheng, Lu,Zhan, Yulin,Yu, Chengyuan,et al. Controlling Helix Sense at N- and C-Termini in Quinoline Oligoamide Foldamers by beta-Pinene-Derived Pyridyl Moieties[J]. ORGANIC LETTERS,2017,19(6):1482-1485.
APA	Zheng, Lu,Zhan, Yulin,Yu, Chengyuan,Huang, Fu,Wang, Ying,&Jiang, Hua.(2017).Controlling Helix Sense at N- and C-Termini in Quinoline Oligoamide Foldamers by beta-Pinene-Derived Pyridyl Moieties.ORGANIC LETTERS,19(6),1482-1485.
MLA	Zheng, Lu,et al."Controlling Helix Sense at N- and C-Termini in Quinoline Oligoamide Foldamers by beta-Pinene-Derived Pyridyl Moieties".ORGANIC LETTERS 19.6(2017):1482-1485.