Stimuli-Responsive Dipeptide-Protein Hydrogels through Schiff Base Coassembly

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	Stimuli-Responsive Dipeptide-Protein Hydrogels through Schiff Base Coassembly
	Yuan, Tingting 1,2; Fei, Jinbo 1; Xu, Youqian 1,2; Yang, Xiaoke 1,2; Li, Junbai 1,2
刊名	MACROMOLECULAR RAPID COMMUNICATIONS
	2017-10-01
卷号	38 期号:20
关键词	Dipeptides Hydrogels Molecular Assemblies Proteins Schiff Bases
英文摘要	Different from the conventional irreversible covalent conjugations, a simple and efficient dynamic Schiff base covalent assembly is developed to construct the stable and smart dipeptide-protein hydrogels under mild conditions. Diphenylalanine-hemoglobin hydrogel is chosen to investigate the gelation formation process and mechanism. It is found that such assembled dipeptide-protein hydrogels are sensitive to pH variation, and simultaneously the proteins can be released without changing the native secondary structures from the gels. Furthermore, these adaptive hydrogels can encapsulate a series of small molecules, multicomponent proteins, and functional nanoparticles. These versatile hydrogels may find a great potential in bioapplications.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/41302]
专题	化学研究所_胶体、界面与化学热力学实验室
作者单位	1.Chinese Acad Sci, CAS Key Lab Colloid Interface & Chem Thermodynam, Inst Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Sch Chem & Chem Engn, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Yuan, Tingting,Fei, Jinbo,Xu, Youqian,et al. Stimuli-Responsive Dipeptide-Protein Hydrogels through Schiff Base Coassembly[J]. MACROMOLECULAR RAPID COMMUNICATIONS,2017,38(20).
APA	Yuan, Tingting,Fei, Jinbo,Xu, Youqian,Yang, Xiaoke,&Li, Junbai.(2017).Stimuli-Responsive Dipeptide-Protein Hydrogels through Schiff Base Coassembly.MACROMOLECULAR RAPID COMMUNICATIONS,38(20).
MLA	Yuan, Tingting,et al."Stimuli-Responsive Dipeptide-Protein Hydrogels through Schiff Base Coassembly".MACROMOLECULAR RAPID COMMUNICATIONS 38.20(2017).