Synthesis and glycosidase inhibition of C-7 modified casuarine derivatives | |
Cheng, Bin1,2; Hirokami, Yuki3; Li, Yi-Xian1,2; Kato, Atsushi3; Jia, Yue-Mei1,2; Yu, Chu-Yi1,2,4 | |
刊名 | CHINESE CHEMICAL LETTERS |
2017-08-01 | |
卷号 | 28期号:8页码:1701-1704 |
关键词 | Nitrone Ammonolysis 1 Glycosidase Inhibitors 3-dipolar Cycloaddition Polyhydroxylated Pyrrolizidines |
英文摘要 | A series of C-7 modified analogues of casuarine have been synthesized from sugar-derived nitrone and assayed against various glycosidases. Introduction of C-7 aminomethyl or amide group led to sharp decrease of the inhibitory activities. (C) 2017 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved. |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.iccas.ac.cn/handle/121111/39253] |
专题 | 化学研究所_分子识别与功能实验室 |
作者单位 | 1.Chinese Acad Sci, CAS Res Educ Ctr Excellence Mol Sci, CAS Key Lab Mol Recognit & Funct, Beijing Natl Lab Mol Sci,Inst Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Toyama Univ, Dept Hosp Pharm, Toyama 9300194, Japan 4.Jiangxi Normal Univ, Natl Engn Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China |
推荐引用方式 GB/T 7714 | Cheng, Bin,Hirokami, Yuki,Li, Yi-Xian,et al. Synthesis and glycosidase inhibition of C-7 modified casuarine derivatives[J]. CHINESE CHEMICAL LETTERS,2017,28(8):1701-1704. |
APA | Cheng, Bin,Hirokami, Yuki,Li, Yi-Xian,Kato, Atsushi,Jia, Yue-Mei,&Yu, Chu-Yi.(2017).Synthesis and glycosidase inhibition of C-7 modified casuarine derivatives.CHINESE CHEMICAL LETTERS,28(8),1701-1704. |
MLA | Cheng, Bin,et al."Synthesis and glycosidase inhibition of C-7 modified casuarine derivatives".CHINESE CHEMICAL LETTERS 28.8(2017):1701-1704. |
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