Enhanced stability and fluorescence of mixed-proteins-protectedgold/silver clusters used for mercury ions detection

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	Enhanced stability and fluorescence of mixed-proteins-protectedgold/silver clusters used for mercury ions detection
	Yang, Guanhua 1,2; Zhang, Han 1; Wang, Yueqi 1; Liu, Xianhu 1; Luo, Zhixun 1; Yao, Jiannian 1,2
刊名	SENSORS AND ACTUATORS B-CHEMICAL
	2017-11-01
卷号	251 页码:773-780
关键词	Gold/silver Clusters Mercury Ions Mixed Proteins Chemosensing Bioimaginga
英文摘要	We have synthesized gold/silver nanoclusters (NCs) under the protection of both bovine-serum-albumin (BSA) and lysozyme (Lyz) and found that the NCs protected by the mixed-proteins give rise to largely enhanced stability and fluorescence, enabling promising applications for chemosensing and bioimaging. The enhanced fluorescence of Au NCs was found to be exclusively quenched at the presence of Hg2+ ions with an ultralow detection limit up to similar to 0.7 nM. It is also interesting to find that the BSA-Lyz-Au NCs are nontoxic and available for fluorescence imaging of Hg2+ detection in MCF-7 cells. The low cytotoxicity, good penetrability and fluorescence sensitivity of BSA-Lyz-Au NCs suggest promising biological applications. Similar observations were also addressed for the Ag system, indicating general applicability of this facile strategy based on BSA-Lyz mixed proteins for the protection of metal NCs. (C) 2017 Elsevier B.V. All rights reserved.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/39250]
专题	化学研究所_分子动态与稳态结构实验室
作者单位	1.Chinese Acad Sci, Inst Chem, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Chem, Key Lab Photochem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Yang, Guanhua,Zhang, Han,Wang, Yueqi,et al. Enhanced stability and fluorescence of mixed-proteins-protectedgold/silver clusters used for mercury ions detection[J]. SENSORS AND ACTUATORS B-CHEMICAL,2017,251:773-780.
APA	Yang, Guanhua,Zhang, Han,Wang, Yueqi,Liu, Xianhu,Luo, Zhixun,&Yao, Jiannian.(2017).Enhanced stability and fluorescence of mixed-proteins-protectedgold/silver clusters used for mercury ions detection.SENSORS AND ACTUATORS B-CHEMICAL,251,773-780.
MLA	Yang, Guanhua,et al."Enhanced stability and fluorescence of mixed-proteins-protectedgold/silver clusters used for mercury ions detection".SENSORS AND ACTUATORS B-CHEMICAL 251(2017):773-780.