Graphdiyne Materials as Nanotransducer for in Vivo Photoacoustic Imaging and Photothermal Therapy of Tumor

	Graphdiyne Materials as Nanotransducer for in Vivo Photoacoustic Imaging and Photothermal Therapy of Tumor
	Li, Shengliang; Chen, Yanhuan; Liu, Huibiao; Wang, Yunxia; Liu, Libing; Lv, Fengting; Li, Yuliang; Wang, Shu
刊名	CHEMISTRY OF MATERIALS
	2017-07-25
卷号	29 期号:14 页码:6087-6094
英文摘要	Two-dimensional (2D) all-carbon materials hold great fascination because of their superior properties and promising applications. Herein, we presented the first demonstration for the use of graphdiyne (GDY) as photothermo-acoustic wave nanotransducers for simultaneous effective photoacoustic imaging (PAI) and photothermal therapy (PTT) in living mice. With a large extinction coefficient in near-infrared (NIR) region, upon irradiated by 808 nm laser, GDY not only exhibits a stable photothermal performance with a high photothermal conversion efficiency of 42%, but also provides an excellent photoacoustic response. Owing to its good biocompatibility modified with PEGylation, GDY can be simultaneously used as PAI probe and PTT agent and exhibits an efficient photothermal ablation of cancer cells in living mice. This work opens a new way into the development of 2D graphdiynes as novel theranostic platform for cancer treatment.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/39186]
专题	化学研究所_有机固体实验室
作者单位	Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Organ Solids, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Li, Shengliang,Chen, Yanhuan,Liu, Huibiao,et al. Graphdiyne Materials as Nanotransducer for in Vivo Photoacoustic Imaging and Photothermal Therapy of Tumor[J]. CHEMISTRY OF MATERIALS,2017,29(14):6087-6094.
APA	Li, Shengliang.,Chen, Yanhuan.,Liu, Huibiao.,Wang, Yunxia.,Liu, Libing.,...&Wang, Shu.(2017).Graphdiyne Materials as Nanotransducer for in Vivo Photoacoustic Imaging and Photothermal Therapy of Tumor.CHEMISTRY OF MATERIALS,29(14),6087-6094.
MLA	Li, Shengliang,et al."Graphdiyne Materials as Nanotransducer for in Vivo Photoacoustic Imaging and Photothermal Therapy of Tumor".CHEMISTRY OF MATERIALS 29.14(2017):6087-6094.