Biocompatible Amphiphilic Hydrogel-Solid Dimer Particles as Colloidal Surfactants

	Biocompatible Amphiphilic Hydrogel-Solid Dimer Particles as Colloidal Surfactants
	Chen, Dong 1,2,3; Amstad, Esther 3; Zhao, Chun-Xia 3,5; Cai, Liheng 3; Fan, Jing 3; Chen, Qiushui 3; Hai, Mingtan 3; Koehler, Stephan 3; Zhang, Huidan 3; Liang, Fuxin 6
刊名	ACS NANO
	2017-12-01
卷号	11 期号:12 页码:11978-11985
关键词	Microfluidics Janus Particle Amphiphilic Particle Colloidal Surfactant Pickering Emulsion Hydrogel
英文摘要	Emulsions of two immiscible liquids can slowly coalesce over time when stabilized by surfactant molecules. Pickering emulsions stabilized by colloidal particles can be much more stable. Here, we fabricate biocompatible amphiphilic dimer particles using a hydrogel, a strongly hydrophilic material, and achieve large contrast in the wetting properties of the two bulbs, resulting in enhanced stabilization of emulsions. We generate monodisperse single emulsions of alginate and shellac solution in oil using a flow-focusing microfluidics device. Shellac precipitates from water and forms a solid bulb at the periphery of the droplet when the emulsion is exposed to acid. Molecular interactions result in amphiphilic dimer particles that consist of two joined bulbs: one hydrogel bulb of alginate in water and the other hydrophobic bulb of shellac. Alginate in the hydrogel compartment can be cross-linked using calcium cations to obtain stable particles. Analogous to surfactant molecules at the interface, the resultant amphiphilic particles stand at the water/oil interface with the hydrogel bulb submerged in water and the hydrophobic bulb in oil and are thus able to stabilize both water-in-oil and oil-in-water emulsions, making these amphiphilic hydrogel-solid particles ideal colloidal surfactants for various applications.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/38459]
专题	化学研究所_高分子物理与化学实验室
作者单位	1.Zhejiang Univ, Inst Proc Equipment, Coll Energy Engn, Zheda Rd 38, Hangzhou 310027, Zhejiang, Peoples R China 2.Zhejiang Univ, State Key Lab Fluid Power & Mech Syst, Zheda Rd 38, Hangzhou 310027, Zhejiang, Peoples R China 3.Harvard Univ, John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA 4.Harvard Univ, Dept Phys, Cambridge, MA 02138 USA 5.Univ Queensland, Australian Inst Bioengn & Nanotechnol, St Lucia, Qld 4072, Australia 6.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Chen, Dong,Amstad, Esther,Zhao, Chun-Xia,et al. Biocompatible Amphiphilic Hydrogel-Solid Dimer Particles as Colloidal Surfactants[J]. ACS NANO,2017,11(12):11978-11985.
APA	Chen, Dong.,Amstad, Esther.,Zhao, Chun-Xia.,Cai, Liheng.,Fan, Jing.,...&Weitz, David A..(2017).Biocompatible Amphiphilic Hydrogel-Solid Dimer Particles as Colloidal Surfactants.ACS NANO,11(12),11978-11985.
MLA	Chen, Dong,et al."Biocompatible Amphiphilic Hydrogel-Solid Dimer Particles as Colloidal Surfactants".ACS NANO 11.12(2017):11978-11985.