Alkaloid constituents from Viola tianschanica | |
Chen, QB (Chen, Qi-Bin); Aisa, HA (Aisa, Haji Akber); Aisa, HA | |
刊名 | PHYTOCHEMISTRY
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2017 | |
卷号 | 144期号:12页码:233-242 |
关键词 | Viola Tianshanica Violaceae Alkaloids Menin-mll1 Protein-protein Interaction Inhibitory Effect |
DOI | 10.1016/j.phytochem.2017.09.011 |
英文摘要 | Eighteen previously undescribed alkaloids, tishaviolamines A-J, including eight pairs of enantiomers, together with two known benzylisoquinoline alkaloids, (-)-bicuculline and (-)-corlumine, were isolated from Viola tianschanica. Among them, tishaviolamine A-E were demonstrated to possess three types of unpresented skeletons. The structures of these alkaloids were established by comprehensive analyses of the 1D, 2D-NMR and (+)HRESIMS data. The absolute configurations of enantiomers were determined by comparing their calculated ECD spectra with the experimental ones. The menin-mixed lineage leukemia 1 protein-protein interaction inhibitory effect of the isolated compounds were also measured. |
WOS记录号 | WOS:000418628100026 |
内容类型 | 期刊论文 |
源URL | [http://ir.xjipc.cas.cn/handle/365002/5120] ![]() |
专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 |
通讯作者 | Aisa, HA |
作者单位 | 1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi 830011, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi 830011, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
推荐引用方式 GB/T 7714 | Chen, QB ,Aisa, HA ,Aisa, HA. Alkaloid constituents from Viola tianschanica[J]. PHYTOCHEMISTRY,2017,144(12):233-242. |
APA | Chen, QB ,Aisa, HA ,&Aisa, HA.(2017).Alkaloid constituents from Viola tianschanica.PHYTOCHEMISTRY,144(12),233-242. |
MLA | Chen, QB ,et al."Alkaloid constituents from Viola tianschanica".PHYTOCHEMISTRY 144.12(2017):233-242. |
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