Molecularly imprinted polymers prepared using a porogenic solvent of an ionic liquid and a macromolecular crowding agent and their application in purification of oleanic acid

doi:10.1039/c5ay01960e

CORC > 新疆理化技术研究所 > 中国科学院新疆理化技术研究所 > 省部共建新疆特有药用资源利用重点实验室

	Molecularly imprinted polymers prepared using a porogenic solvent of an ionic liquid and a macromolecular crowding agent and their application in purification of oleanic acid
	Zhang, C (Zhang, Chen)1; Li, F (Li, Fang)1; Wang, SX (Wang, Si-Xi)1; Liu, ZS (Liu, Zhao-Sheng)1; Aisa, HA (Aisa, Haji Akber)1
刊名	ANALYTICAL METHODS
	2015
卷号	7 期号:24 页码:10256-10265
DOI	10.1039/c5ay01960e
英文摘要	A strategy to increase the affinity of molecularly imprinted polymers (MIPs) using a novel porogenic solvent was described based on the cooperative effect of ionic liquids and macromolecular crowding agents. A typical porogenic solvent is composed of a ternary mixture of polymethylmethacrylate (PMAA) solution in chloroform, dimethyl sulfoxide and 1-butyl-3-methylimidazolium tetrafluoroborate. The method can produce 4-vinylpyridine-based MIP monoliths with good permeability. The influence of some important polymerization variables, i.e., PMMA concentration, the type of ionic liquid and crowding agent, and the ratio between PMMA and the ionic liquid, on the imprinting performance was studied. The cooperative effect of the macromolecular crowding agent and ionic liquid was demonstrated by comparing the imprinting effect of the MIPs with other polymers made with only the macromolecular crowding agent or ionic liquid. The type of macromolecular crowding agent and ionic liquid has significantly influenced the imprinting performance of the achieved MIPs. The resulting oleanic acid (OA) MIP can be used to purify OA from the crude extract efficiently with a mean recovery of 72.32%.
WOS记录号	WOS:000365912900023
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/4995]
专题	新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室
作者单位	1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Xinjiang 830011, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Xinjiang 830011, Peoples R China
推荐引用方式 GB/T 7714	Zhang, C ,Li, F ,Wang, SX ,et al. Molecularly imprinted polymers prepared using a porogenic solvent of an ionic liquid and a macromolecular crowding agent and their application in purification of oleanic acid[J]. ANALYTICAL METHODS,2015,7(24):10256-10265.
APA	Zhang, C ,Li, F ,Wang, SX ,Liu, ZS ,&Aisa, HA .(2015).Molecularly imprinted polymers prepared using a porogenic solvent of an ionic liquid and a macromolecular crowding agent and their application in purification of oleanic acid.ANALYTICAL METHODS,7(24),10256-10265.
MLA	Zhang, C ,et al."Molecularly imprinted polymers prepared using a porogenic solvent of an ionic liquid and a macromolecular crowding agent and their application in purification of oleanic acid".ANALYTICAL METHODS 7.24(2015):10256-10265.