Backbone and side-chain chemical shift assignments of MarH, a critical intermediary epimerase for biosynthesis of Maremycins in Streptomyces
Liu, Bin1,2; Fang, Shiqi1,2; Ma, Xiaofang1,2; Bai, Zhiqiang1,2; Hu, Kaifeng1
刊名BIOMOLECULAR NMR ASSIGNMENTS
2018-10-01
卷号12期号:2页码:335-338
关键词MarH Epimerase NMR Chemical shift assignments
ISSN号1874-2718
DOI10.1007/s12104-018-9835-2
英文摘要MarH is an essential epimerase that catalyzes the isomerization of 3R--methyl-indolepyruvate (-MeInPy) to 3S--MeInPy, which is the important precursor for biosynthesis of Maremycins. Biophysical study of the structure of MarH would be informative for better understanding of its catalytic mechanism and feasible application of the enzyme in isomerization reaction. Here, we report the backbone and side-chain NMR chemical shift assignments of MarH, which lays a foundation for further structural and mechanical study of the enzyme.
资助项目National Key Research and Development Program of China[2017YFC0906900] ; National Natural Science Foundation of China[21573258] ; Yunnan Provincial Science and Technology Department[2015FA028]
WOS研究方向Biophysics ; Spectroscopy
语种英语
出版者SPRINGER
WOS记录号WOS:000443824500022
资助机构National Key Research and Development Program of China ; National Natural Science Foundation of China ; Yunnan Provincial Science and Technology Department
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/62303]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者Hu, Kaifeng
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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GB/T 7714
Liu, Bin,Fang, Shiqi,Ma, Xiaofang,et al. Backbone and side-chain chemical shift assignments of MarH, a critical intermediary epimerase for biosynthesis of Maremycins in Streptomyces[J]. BIOMOLECULAR NMR ASSIGNMENTS,2018,12(2):335-338.
APA Liu, Bin,Fang, Shiqi,Ma, Xiaofang,Bai, Zhiqiang,&Hu, Kaifeng.(2018).Backbone and side-chain chemical shift assignments of MarH, a critical intermediary epimerase for biosynthesis of Maremycins in Streptomyces.BIOMOLECULAR NMR ASSIGNMENTS,12(2),335-338.
MLA Liu, Bin,et al."Backbone and side-chain chemical shift assignments of MarH, a critical intermediary epimerase for biosynthesis of Maremycins in Streptomyces".BIOMOLECULAR NMR ASSIGNMENTS 12.2(2018):335-338.
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