Chromanopyrones and a flavone from Hypericum monogynum

doi:10.1016/j.fitote.2017.12.013

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Chromanopyrones and a flavone from Hypericum monogynum
	Zeng, Yan-Rong 1,2,3; Wang, Li-Ping 1,2,3; Hu, Zhan-Xing1,3 ; Yi, Ping 1,2,3; Yang, Wan-Xia 1,2,3; Gu, Wei1,2,3 ; Huang, Lie-Jun 1,2,3; Yuan, Chun-Mao 1,2,3; Hao, Xiao-Jiang1,2,3,4
刊名	FITOTERAPIA
	2018-03-01
卷号	125 页码:59-64
关键词	Hypericum Monogynum Pyrone Derivatives Inhibitory Effects On Alpha-glucosidase Anti-oxidant Activity
ISSN号	0367-326X
DOI	10.1016/j.fitote.2017.12.013
英文摘要	Six new compounds, including three pyrone derivatives (2-4), one new flavone (5), and two new naturally-occurring compounds (1 and 6), together with 16 known compounds were isolated from the leaves and twigs of Hypericum monogynum. In addition, compounds 2-4 are racemates. Their structures and absolute configurations were determined on the basis of extensive analysis of spectroscopic data and ECD calculation. All compounds were evaluated for the inhibitory effects on alpha-glucosidase, compounds 1, 5, and 7 showed moderate inhibitory activities with IC50 values of 161.46, 257.78, and 11.54 mu g/ml, respectively. Compound 8 exhibited weak antioxidant activity with IC50 value of 12.55 mu g/ml.
语种	英语
WOS记录号	WOS:000425560500010
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/60549]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Guizhou, Peoples R China 2.Guizhou Med Univ, Sch Pharmacuet Sci, Guiyang 550025, Guizhou, Peoples R China 3.Chinese Acad Sci, Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550014, Guizhou, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Zeng, Yan-Rong,Wang, Li-Ping,Hu, Zhan-Xing,et al. Chromanopyrones and a flavone from Hypericum monogynum[J]. FITOTERAPIA,2018,125:59-64.
APA	Zeng, Yan-Rong.,Wang, Li-Ping.,Hu, Zhan-Xing.,Yi, Ping.,Yang, Wan-Xia.,...&Hao, Xiao-Jiang.(2018).Chromanopyrones and a flavone from Hypericum monogynum.FITOTERAPIA,125,59-64.
MLA	Zeng, Yan-Rong,et al."Chromanopyrones and a flavone from Hypericum monogynum".FITOTERAPIA 125(2018):59-64.