New pregnane saponins from Ecdysanthera rosea and their cytotoxicity

doi:10.1016/j.fitote.2011.01.022

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 中国科学院东亚植物多样性与生物地理学重点实验室

	New pregnane saponins from Ecdysanthera rosea and their cytotoxicity
	Zhu, Xiangdong 1,2; Wu, Guisheng1 ; Xiang, Jianying 3; Luo, Huairong1 ; Luo, Shide 1; Zhu, Hongmei 4; Wang, Yifen1
刊名	FITOTERAPIA
	2011-06-01
卷号	82 期号:4 页码:632-636
关键词	Ecdysanthera Rosea Pregnane Saponin Ecdysantheroside b Cytotoxicity
ISSN号	0367-326X
DOI	10.1016/j.fitote.2011.01.022
通讯作者	xdzhu815@yahoo.com.cn ; wangyifen@mail.kib.ac.cn
文献子类	Article
英文摘要	Two new pregnane saponins elucidated as ecdysantheroside A (1) and ecdysantheroside B (2) and six known compounds (3-8) based on spectral data (MS, IR, 1D and 2D NMR) were isolated from the stem bark of Ecdysanthera rosea. The cytotoxicity against six cell lines of these compounds was tested by MTT assay. The results revealed that compounds 5 and 7 showed cytotoxicity against all the cell lines. Compound 2 showed cytotoxicity against cells A549, MDA435, HepG2, and HUVEC, while compound 4 showed cytotoxicity against cells A549, CEM, and HUVEC. Compound 6 had cytotoxicity against the others except cell HepG2. (C) 2011 Elsevier B.V. All rights reserved.
学科主题	Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS关键词	GLYCOSIDES ; TRITERPENE
WOS研究方向	Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000291140800018
资助机构	National Natural Science Foundation[30860037, 20872148]; Department of Science and Technology in Yunnan Province[20080A007]
公开日期	2012-03-16
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/3940]
专题	昆明植物研究所_中国科学院东亚植物多样性与生物地理学重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Jiangxi Agr Univ, Coll Biosci & Bioengn, Nanchang 330045, Peoples R China 3.Chinese Acad Sci, Key Lab Biodivers & Biogeog, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 4.Xiamen Univ, Coll Oceanog & Environm Sci, Xiamen 361000, Peoples R China
推荐引用方式 GB/T 7714	Zhu, Xiangdong,Wu, Guisheng,Xiang, Jianying,et al. New pregnane saponins from Ecdysanthera rosea and their cytotoxicity[J]. FITOTERAPIA,2011,82(4):632-636.
APA	Zhu, Xiangdong.,Wu, Guisheng.,Xiang, Jianying.,Luo, Huairong.,Luo, Shide.,...&Wang, Yifen.(2011).New pregnane saponins from Ecdysanthera rosea and their cytotoxicity.FITOTERAPIA,82(4),632-636.
MLA	Zhu, Xiangdong,et al."New pregnane saponins from Ecdysanthera rosea and their cytotoxicity".FITOTERAPIA 82.4(2011):632-636.