Anthraquinones and Lignans from Cassia occidentalis
Li, Shi-Fei1,2; Di, Ying-Tong1; Wang, Yue-Hu1; Tan, Cheng-Jian1; Fang, Xin1; Zhang, Yu1,2; Zheng, Yong-Tang3; Li, Ling4; He, Hong-Ping1; Li, Shun-Lin1
刊名HELVETICA CHIMICA ACTA
2010
卷号93期号:9页码:1795-1802
关键词Derivatives Mandshurica Fruit
ISSN号0018-019X
文献子类Article
英文摘要One new anthraquinone glycoside. 6-O-(alpha-L-rhamnopyranosyl (1 -> 6)-beta-D-glucopyranosyl)emodin (1). and two new sesquilignans. seslignanoccidentaliols A (2) and B (3), were isolated from the whole plant of Cassia occidentalis. The structures of the new compounds were established by means of spectroscopic methods, especially 2D-NMR data ((1)H.(1)H-COSY. HMQC, HMBC. and ROESY). as well as HR-ESI-MS analysis. One previously reported sesquilignan. crythro-guaiacylglycerol-beta-O-4'-(5')-methoxylariciresinol, was revised to be seslignanoccidentaliol A (2). The 6-O-(alpha-L-rhamnopyranosyl(1 -> 6)-beta-D-glucopyranosyl)emodin (1) exhibited moderate anti HIV-1 activity with an EC(50) value of 2.90 mu g/ml and a therapeutic-index (TI) value of 260.
学科主题Chemistry, Multidisciplinary
WOS关键词MAGNOLIA-FARGESII ; FLOWER BUDS ; GLYCOSIDES ; STEREOISOMERS ; NEOLIGNANS
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000283273200015
资助机构National Natural Science Foundation of China [30760306]; Yunnan Provincial Science Foundation [2006C009Z]
公开日期2012-03-21
内容类型期刊论文
源URL[http://ir.kib.ac.cn:8080/handle/151853/4958]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Botany, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Lab Mol Immunopharmacol, Kunming Inst Zool, Kunming 650223, Peoples R China
4.Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming 650031, Peoples R China
推荐引用方式
GB/T 7714
Li, Shi-Fei,Di, Ying-Tong,Wang, Yue-Hu,et al. Anthraquinones and Lignans from Cassia occidentalis[J]. HELVETICA CHIMICA ACTA,2010,93(9):1795-1802.
APA Li, Shi-Fei.,Di, Ying-Tong.,Wang, Yue-Hu.,Tan, Cheng-Jian.,Fang, Xin.,...&Hao, Xiao-Jiang.(2010).Anthraquinones and Lignans from Cassia occidentalis.HELVETICA CHIMICA ACTA,93(9),1795-1802.
MLA Li, Shi-Fei,et al."Anthraquinones and Lignans from Cassia occidentalis".HELVETICA CHIMICA ACTA 93.9(2010):1795-1802.
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