Bi-linderone, a Highly Modified Methyl-linderone Dimer from Lindera aggregata with Activity toward Improvement of Insulin Sensitivity in Vitro | |
Wang, Fei1,2; Gao, Yuan2; Zhang, Ling1; Liu, Ji-Kai1 | |
刊名 | ORGANIC LETTERS
![]() |
2010-05-21 | |
卷号 | 12期号:10页码:2354-2357 |
关键词 | Sesquiterpene Lactones Water Extract Strychnifolia Root Butanolides |
ISSN号 | 1523-7060 |
DOI | 10.1021/ol1007247 |
文献子类 | Article |
英文摘要 | Bi-linderone (1) was isolated as racemate from the traditional Chinese medicinal plant Lindera aggregata. The structure elucidation of bi-linderone was reported on the basis of extensive analysis of NMR spectra and crystal X-ray diffraction. Bi-linderone has an unprecedented spirocyclopentenedione-containing carbon skeleton and showed significant activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 mu g/mL. |
学科主题 | Chemistry, Organic |
WOS关键词 | SESQUITERPENE LACTONES ; WATER EXTRACT ; STRYCHNIFOLIA ; ROOT ; BUTANOLIDES |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000277531000047 |
资助机构 | National Basic Research Program of China [2009CB522300]; National Natural Science Foundation of China [30830113]; MOST [2009ZX09501-029, 2009ZX09501-013] |
公开日期 | 2012-03-21 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn:8080/handle/151853/4284] ![]() |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.BioBioPha Co Ltd, Kunming 656204, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Fei,Gao, Yuan,Zhang, Ling,et al. Bi-linderone, a Highly Modified Methyl-linderone Dimer from Lindera aggregata with Activity toward Improvement of Insulin Sensitivity in Vitro[J]. ORGANIC LETTERS,2010,12(10):2354-2357. |
APA | Wang, Fei,Gao, Yuan,Zhang, Ling,&Liu, Ji-Kai.(2010).Bi-linderone, a Highly Modified Methyl-linderone Dimer from Lindera aggregata with Activity toward Improvement of Insulin Sensitivity in Vitro.ORGANIC LETTERS,12(10),2354-2357. |
MLA | Wang, Fei,et al."Bi-linderone, a Highly Modified Methyl-linderone Dimer from Lindera aggregata with Activity toward Improvement of Insulin Sensitivity in Vitro".ORGANIC LETTERS 12.10(2010):2354-2357. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论