Two new taxoids from Taxus chinensis

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Two new taxoids from Taxus chinensis
	Xia, ZH ; Peng, LY ; Zhao, Y ; Xu, G; Zhao, QS; Sun, HD
刊名	CHEMISTRY & BIODIVERSITY
	2005
卷号	2 期号:10 页码:1316-1319
关键词	Oxetane-ring Taxanes Mairei Roots
ISSN号	1612-1872
文献子类	Article
英文摘要	Two new taxoids, 2,20-O-diacetyltaxumairol N (1) and 14 beta-hydroxy-10-deacetyl-2-O-debenzoylbacatin III (2), were isolated from the needles and stems of Taxus chinensis. Their structures were determined on the basis of extensive 1D- and 2D-NMR-spectral analysis. Compound 1 showed weak cytotoxicity activity against T-24 (IC50 = 34 mu g/ml) and QGY-7701 (IC50 = 22 mu g/ml) cancer lines. Compound 2 showed no obvious cytotoxicity activity against T-24 (IC50 > 100 mu g/ml) and QGY-7701 (IC50 > 100 mu g/ml) cancer lines.
学科主题	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS关键词	OXETANE-RING ; TAXANES ; MAIREI ; ROOTS
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
WOS记录号	WOS:000233147400005
公开日期	2012-03-21
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/4046]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Kunming 650204, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Xia, ZH,Peng, LY,Zhao, Y,et al. Two new taxoids from Taxus chinensis[J]. CHEMISTRY & BIODIVERSITY,2005,2(10):1316-1319.
APA	Xia, ZH,Peng, LY,Zhao, Y,Xu, G,Zhao, QS,&Sun, HD.(2005).Two new taxoids from Taxus chinensis.CHEMISTRY & BIODIVERSITY,2(10),1316-1319.
MLA	Xia, ZH,et al."Two new taxoids from Taxus chinensis".CHEMISTRY & BIODIVERSITY 2.10(2005):1316-1319.