Cytotoxic macrocyclic diterpenoids from Euphorbia helioscopia | |
Tao, Hong-Wen; Hao, Xiao-Jiang2![]() | |
刊名 | ARCHIVES OF PHARMACAL RESEARCH
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2008-12-01 | |
卷号 | 31期号:12页码:1547-1551 |
关键词 | Diterpenoid Euphornin l X-ray Euphorbia Helioscopia l Cytotoxicity |
ISSN号 | 0253-6269 |
DOI | 10.1007/s12272-001-2149-3 |
文献子类 | Article |
英文摘要 | A new cytotoxic macrocyclic diterpenoid, euphornin L (1), together with seven known analogues were isolated from the plant Euphorbia helioscopia L. The structure of 1 was elucidated by spectral data and X-ray crystallographic analysis. Euphornin L (1) and euphoscopin F (2) exhibited significant cytotoxicity against HL-60 cell lines with IC(50) values of 2.7 and 9.0 mu M, respectively. The (13)C-NMR data of euphoscopin F (2), epieuphoscopin B (3), euphoscopin B (5), and euphoscopin C (6) were also reported for the first time. |
学科主题 | Chemistry ; Medicinal ; Pharmacology & Pharmacy |
WOS关键词 | ASSAY |
WOS研究方向 | Pharmacology & Pharmacy |
语种 | 英语 |
WOS记录号 | WOS:000261938900005 |
资助机构 | Chinese National Programs for High Technology Research and Development [2007AA091502, 2007AA09z447]; Shanghai Institute of Materia Medica ; Chinese Academy of Sciences |
公开日期 | 2011-11-24 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn:8080/handle/151853/1753] ![]() |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Ocean Univ China, Sch Med & Pharm, Qingdao 266003, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China |
推荐引用方式 GB/T 7714 | Tao, Hong-Wen,Hao, Xiao-Jiang,Liu, Pei-Pei,et al. Cytotoxic macrocyclic diterpenoids from Euphorbia helioscopia[J]. ARCHIVES OF PHARMACAL RESEARCH,2008,31(12):1547-1551. |
APA | Tao, Hong-Wen,Hao, Xiao-Jiang,Liu, Pei-Pei,&Zhu, Wei-Ming.(2008).Cytotoxic macrocyclic diterpenoids from Euphorbia helioscopia.ARCHIVES OF PHARMACAL RESEARCH,31(12),1547-1551. |
MLA | Tao, Hong-Wen,et al."Cytotoxic macrocyclic diterpenoids from Euphorbia helioscopia".ARCHIVES OF PHARMACAL RESEARCH 31.12(2008):1547-1551. |
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