Phytochemical and genetic analyses of ancient cannabis from Central Asia

doi:10.1093/jxb/ern260

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Phytochemical and genetic analyses of ancient cannabis from Central Asia
	Russo, Ethan B.1,2; Jiang, Hong-En 3,4; Li, Xiao 4; Sutton, Alan 1; Carboni, Andrea 5; del Bianco, Francesca 5; Mandolino, Giuseppe 5; Potter, David J.1; Zhao, You-Xing 6; Bera, Subir 7
刊名	JOURNAL OF EXPERIMENTAL BOTANY
	2008-11-01
卷号	59 期号:15 页码:4171-4182
关键词	Yanghai Tombs Sativa l China Dna Amplification Cannabaceae Xinjiang
ISSN号	0022-0957
DOI	10.1093/jxb/ern260
文献子类	Article
英文摘要	The Yanghai Tombs near Turpan, Xinjiang-Uighur Autonomous Region, China have recently been excavated to reveal the 2700-year-old grave of a Caucasoid shaman whose accoutrements included a large cache of cannabis, superbly preserved by climatic and burial conditions. A multidisciplinary international team demonstrated through botanical examination, phytochemical investigation, and genetic deoxyribonucleic acid analysis by polymerase chain reaction that this material contained tetrahydrocannabinol, the psychoactive component of cannabis, its oxidative degradation product, cannabinol, other metabolites, and its synthetic enzyme, tetrahydrocannabinolic acid synthase, as well as a novel genetic variant with two single nucleotide polymorphisms. The cannabis was presumably employed by this culture as a medicinal or psychoactive agent, or an aid to divination. To our knowledge, these investigations provide the oldest documentation of cannabis as a pharmacologically active agent, and contribute to the medical and archaeological record of this pre-Silk Road culture.
学科主题	Plant Sciences
WOS关键词	YANGHAI TOMBS ; SATIVA L ; CANNABACEAE ; CHINA ; DNA ; AMPLIFICATION ; XINJIANG
WOS研究方向	Plant Sciences
语种	英语
WOS记录号	WOS:000261280000010
资助机构	Chinese Academy of Sciences ; GW Pharmaceuticals
公开日期	2011-11-24
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/1735]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.GW Pharmaceut, Salisbury SP4 0JQ, Wilts, England 2.Univ Montana, Fac Affiliate, Dept Pharmaceut Sci, Missoula, MT 59812 USA 3.Chinese Acad Sci, Inst Bot, Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China 4.Bur Cultural Rel Turpan Prefecture, Turpan 838000, Xinjiang, Peoples R China 5.CRA Ctr Recerca Colture Ind, I-40128 Bologna, Italy 6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 7.Univ Calcutta, Dept Bot, Kolkata 700019, W Bengal, India 8.Xinjiang Inst Archaeol, Urumqi 830011, Xinjiang, Peoples R China 9.Univ Vienna, Inst Palaeontol, A-1090 Vienna, Austria 10.Smithsonian Inst, Dept Paleobiol, Washington, DC 20560 USA
推荐引用方式 GB/T 7714	Russo, Ethan B.,Jiang, Hong-En,Li, Xiao,et al. Phytochemical and genetic analyses of ancient cannabis from Central Asia[J]. JOURNAL OF EXPERIMENTAL BOTANY,2008,59(15):4171-4182.
APA	Russo, Ethan B..,Jiang, Hong-En.,Li, Xiao.,Sutton, Alan.,Carboni, Andrea.,...&Li, Cheng-Sen.(2008).Phytochemical and genetic analyses of ancient cannabis from Central Asia.JOURNAL OF EXPERIMENTAL BOTANY,59(15),4171-4182.
MLA	Russo, Ethan B.,et al."Phytochemical and genetic analyses of ancient cannabis from Central Asia".JOURNAL OF EXPERIMENTAL BOTANY 59.15(2008):4171-4182.