Alkaloids from Melodinus yunnanensis

doi:10.1016/j.phytochem.2012.06.013

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Alkaloids from Melodinus yunnanensis
	Cai, Xiang-Hai; Li, Yan; Liu, Ya-Ping; Li, Xiao-Ning; Bao, Mei-Fen; Luo, Xiao-Dong
刊名	PHYTOCHEMISTRY
	2012-11-01
卷号	83 页码:116-124
关键词	Melodinus Yunnanensis Apocynaceae Monoterpenoid Indole Alkaloid Structure Elucidation Cytotoxicity
ISSN号	0031-9422
DOI	10.1016/j.phytochem.2012.06.013
通讯作者	Cai, XH (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China.,xhcai@mail.kib.ac.cn ; xdluo@mail.kib.ac.cn
文献子类	Article
英文摘要	Ten monoterpenoid indole alkaloids, namely meloyine, 19S-methoxytubotaiwine N-4-oxide, 16,19-epoxy-Delta(14)-vincanol, 14 beta-hydroxymeloyunine, meloyunine, Delta(14)-vincamenine N-4-oxide, 16 beta,21 beta-epoxy-vincadine, 14 beta,15 beta-20S-quebrachamine, 3-oxo-voaphylline, 2 alpha,7 alpha-dihydroxy-dihydrovoaphylline, and 32 known alkaloids were isolated from leaves and twigs of Melodious yunnanensis. Their structures were elucidated based on 1- and 2-D NMR, FTIR, UV, and MS spectroscopic data. Meloyine I showed weak cytotoxic activity against four human cancer cell lines: MCF-7 breast cancer, SMMC-7721 hepatocellular carcinoma, HL-60 myeloid leukemia, and A-549 lung cancer. (C) 2012 Elsevier Ltd. All rights reserved.
学科主题	Biochemistry & Molecular Biology ; Plant Sciences
WOS关键词	CYTOTOXIC INDOLE ALKALOIDS ; ASPIDOSPERMA-TYPE ; NEW-CALEDONIA ; PLANTS ; HENRYI ; TABERNAEMONTANA ; TENUICAUDATUS ; CELASTROIDES ; VOAPHYLLINE ; DIVARICATA
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences
语种	英语
WOS记录号	WOS:000310421100014
资助机构	National Natural Science Foundation of China [2107298, 21172225, 31170334]; Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI049]; 973 Program of the Ministry of Science and Technology of P.R. China [2009CB522300]; Chinese Academy of Sciences (XiBuZhiGuang Project)
公开日期	2013-01-22
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/15934]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Cai, Xiang-Hai,Li, Yan,Liu, Ya-Ping,et al. Alkaloids from Melodinus yunnanensis[J]. PHYTOCHEMISTRY,2012,83:116-124.
APA	Cai, Xiang-Hai,Li, Yan,Liu, Ya-Ping,Li, Xiao-Ning,Bao, Mei-Fen,&Luo, Xiao-Dong.(2012).Alkaloids from Melodinus yunnanensis.PHYTOCHEMISTRY,83,116-124.
MLA	Cai, Xiang-Hai,et al."Alkaloids from Melodinus yunnanensis".PHYTOCHEMISTRY 83(2012):116-124.