Four New ent-Kauranoids from Isodon rubescens var. lushanensis and Data Reassignment of Dayecrystal B

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Four New ent-Kauranoids from Isodon rubescens var. lushanensis and Data Reassignment of Dayecrystal B
	Zhang, Ha-Bo 1,2; Pu, Jian-Xin1 ; Wang, Yuan-Yuan 1; He, Fei 1,2; Zhao, Yong 1; Li, Xiao-Nian 1,2; Luo, Xiao 1,2; Xiao, Wei-Lie 1; Li, Yan1 ; Sun, Han-Dong1
刊名	CHEMICAL & PHARMACEUTICAL BULLETIN
	2010
卷号	58 期号:1 页码:56-60
关键词	Isodon Rubescens Var. Lushanensis Ent-kauranoid Cytotoxicity
ISSN号	0009-2363
文献子类	Article
英文摘要	Four new 7, 20-epoxy-ent-kauranoids, rubluanins A-D (1-4) and eleven known ones, were isolated from Isodon rubescens var. lushanensis, and their structures were elucidated by spectroscopic analysis. Compounds 2-14 were evaluated for their cytotoxicity in several human tumor cell lines (U937, Jurkat, HL-60, K562, SGC790, and HepG2). Among the compounds, lasiokaurin (13) showed significant cytotoxic activity of 0.62 mu M (IC50) in U937 cells.
学科主题	Chemistry ; Medicinal ; Multidisciplinary ; Chemistry ; Pharmacology & Pharmacy
WOS关键词	A-C ; DITERPENOIDS ; JAPONICUS ; DIMERS
WOS研究方向	Pharmacology & Pharmacy ; Chemistry
语种	英语
WOS记录号	WOS:000273168400011
资助机构	NSFC [30772637, 30830119]; NSFC-Joint Foundation of Yunnan Province [U0832602]; Major State Basic Research Development Program of China [2009CB522300, 2009CB940900]; Natural Science Foundation of Yunnan Province [2008CD162]; CAS [KSCX2-YW-R-25]
公开日期	2011-11-24
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/1503]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Ha-Bo,Pu, Jian-Xin,Wang, Yuan-Yuan,et al. Four New ent-Kauranoids from Isodon rubescens var. lushanensis and Data Reassignment of Dayecrystal B[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2010,58(1):56-60.
APA	Zhang, Ha-Bo.,Pu, Jian-Xin.,Wang, Yuan-Yuan.,He, Fei.,Zhao, Yong.,...&Sun, Han-Dong.(2010).Four New ent-Kauranoids from Isodon rubescens var. lushanensis and Data Reassignment of Dayecrystal B.CHEMICAL & PHARMACEUTICAL BULLETIN,58(1),56-60.
MLA	Zhang, Ha-Bo,et al."Four New ent-Kauranoids from Isodon rubescens var. lushanensis and Data Reassignment of Dayecrystal B".CHEMICAL & PHARMACEUTICAL BULLETIN 58.1(2010):56-60.