Cytotoxic steroidal saponins from Polygonatum punctatum

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	Cytotoxic steroidal saponins from Polygonatum punctatum
	Yang, Qing-Xiong ; Yang, Chong-Ren
刊名	CHEMISTRY & BIODIVERSITY
	2006
卷号	3 期号:12 页码:1349-1355
关键词	Ophiopogonis Tuber Subterranean Part Constituents Congeners
ISSN号	1612-1872
文献子类	Article
英文摘要	Four new steroidal saponins, polypunctosides A-D (1-4, resp.), were isolated from the rhizomes of Polygonatum punctatum, together with five known steroidal saponins. On the basis of chemical and spectral evidence, the structures of the new saponins were established as (3 beta,23S,25R)-23-(alpha-L-arabinopyranosyloxy)spirost-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-D-glucopyranoside (1), (3 beta,23S,25R)-23-[ (2-O-acetyl-alpha-L-arabinopyranosyl)oxy]spirost-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-D-glucopyranoside (2), (3 beta,23S,25R)-23-[(3-O-acetyl-alpha-L-arabinopyranosyl)oxy]spirost-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-D-glucopyranoside (3), and (3 beta,23S,25R)-23-[(4-O-acetyl-alpha-L-arabinopyranosyl)oxy]spirost-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-D-glucopyranoside (4). The cytotoxic activity of the isolated saponins was evaluated towards HeLa cells.
学科主题	Biochemistry & Molecular Biology ; Chemistry ; Multidisciplinary
WOS关键词	OPHIOPOGONIS TUBER ; SUBTERRANEAN PART ; CONSTITUENTS ; CONGENERS
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
WOS记录号	WOS:000243372200007
公开日期	2011-11-24
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/1481]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Guizhou Normal Univ, Coll Biotechnol & Bioengn, Guiyang 550001, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Yang, Qing-Xiong,Yang, Chong-Ren. Cytotoxic steroidal saponins from Polygonatum punctatum[J]. CHEMISTRY & BIODIVERSITY,2006,3(12):1349-1355.
APA	Yang, Qing-Xiong,&Yang, Chong-Ren.(2006).Cytotoxic steroidal saponins from Polygonatum punctatum.CHEMISTRY & BIODIVERSITY,3(12),1349-1355.
MLA	Yang, Qing-Xiong,et al."Cytotoxic steroidal saponins from Polygonatum punctatum".CHEMISTRY & BIODIVERSITY 3.12(2006):1349-1355.