Phosphine-Catalyzed Enantioselective [4+3] Annulation of Allenoates with C,N-Cyclic Azomethine Imines: Synthesis of Quinazoline-Based Tricyclic Heterocycles

doi:10.1021/acs.orglett.6b02885

	Phosphine-Catalyzed Enantioselective [4+3] Annulation of Allenoates with C,N-Cyclic Azomethine Imines: Synthesis of Quinazoline-Based Tricyclic Heterocycles
	Yuan, CH; Zhou, LJ; Xia MR(夏苗仁); Wang DQ(王东琪); Xia, MR; Sun, ZH; Wang, DQ; Guo, HC; Wang, Dongqi; Xia, Miaoren
刊名	ORGANIC LETTERS
	2016
卷号	18 期号:21 页码:5644-5647
DOI	10.1021/acs.orglett.6b02885
英文摘要	With the use of a commercially available chiral phosphine as the catalyst, the first catalytic enantioselective [4 + 3] annulation of allenoates with C,N-cyclic azomethine imines is developed. The reaction works efficiently under mild reaction conditions to afford seven-membered ring-fused quinazoline-based tricyclic heterocycles in high yields with good to excellent diastereo- and enantioselectivities.
语种	英语
WOS记录号	WOS:000387303200050
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/260414]
专题	中国科学院高能物理研究所
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Yuan, CH,Zhou, LJ,Xia MR,et al. Phosphine-Catalyzed Enantioselective [4+3] Annulation of Allenoates with C,N-Cyclic Azomethine Imines: Synthesis of Quinazoline-Based Tricyclic Heterocycles[J]. ORGANIC LETTERS,2016,18(21):5644-5647.
APA	Yuan, CH.,Zhou, LJ.,夏苗仁.,王东琪.,Xia, MR.,...&Xia, Miaoren.(2016).Phosphine-Catalyzed Enantioselective [4+3] Annulation of Allenoates with C,N-Cyclic Azomethine Imines: Synthesis of Quinazoline-Based Tricyclic Heterocycles.ORGANIC LETTERS,18(21),5644-5647.
MLA	Yuan, CH,et al."Phosphine-Catalyzed Enantioselective [4+3] Annulation of Allenoates with C,N-Cyclic Azomethine Imines: Synthesis of Quinazoline-Based Tricyclic Heterocycles".ORGANIC LETTERS 18.21(2016):5644-5647.