Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments | |
Shu, Yao-Gen; Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan; Lai, Pik-Yin | |
刊名 | JOURNAL OF PHYSICAL CHEMISTRY B |
2008 | |
卷号 | 112期号:42页码:13453-13459 |
关键词 | 3 Catalytic Sites Bovine Heart-mitochondria Atp Synthase Catalysis Escherichia-coli Substrate-binding Molecular Motors Proton-transport Oxidative-phosphorylation Energy Transduction F1f0-atp Synthase |
ISSN号 | 1520-6106 |
英文摘要 | The systematic kinetics of the holoenzyme FoF1-ATPase has been investigated by a tri-site filled, random binding order, and stochastic mechanochemical tight coupling model. The connection between the mechanical rotation speed and the chemical quantities such as the concentrations of substrates, the proton motive force, and the mechanical damping coefficient, has been analytically derived. The enzymatics based on ensemble experiments and single-molecule assays can be discussed systematically. Our model predictions agree well with both ensemble and single-molecule experimental results. Furthermore, this model can be used to study the dynamics of FoF1-ATPase in a vesicle system. |
学科主题 | Physics |
URL标识 | 查看原文 |
WOS记录号 | WOS:000260100900039 |
公开日期 | 2012-08-02 |
内容类型 | 期刊论文 |
源URL | [http://ir.itp.ac.cn/handle/311006/5447] |
专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
通讯作者 | Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan |
推荐引用方式 GB/T 7714 | Shu, Yao-Gen,Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan,Lai, Pik-Yin. Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2008,112(42):13453-13459. |
APA | Shu, Yao-Gen,Shu, YG , Natl Cent Univ, Grad Inst Biophys, Dept Phys, Chungli 320, Taiwan,&Lai, Pik-Yin.(2008).Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments.JOURNAL OF PHYSICAL CHEMISTRY B,112(42),13453-13459. |
MLA | Shu, Yao-Gen,et al."Systematic Kinetics Study of FoF1-ATPase: Analytic Results and Comparison with Experiments".JOURNAL OF PHYSICAL CHEMISTRY B 112.42(2008):13453-13459. |
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