Health risks associated with genetic alterations in internal clock system by external factors

doi:10.7150/ijbs.23744

CORC > 地质与地球物理研究所 > 中国科学院地质与地球物理研究所 > 兰州油气中心

	Health risks associated with genetic alterations in internal clock system by external factors
	Khan, Suliman 1,2,3; Nabi, Ghulam 1,3; Yao, Lunguang 2; Siddique, Rabeea 4,5; Sajjad, Wasim 3,6; Kumar, Sunjeet 1; Duan, Pengfei 2; Hou, Hongwei 1
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
	2018
卷号	14 期号:7 页码:791-798
关键词	Circadian system sleep health risks clock genes
ISSN号	1449-2288
DOI	10.7150/ijbs.23744
文献子类	Review
英文摘要	The circadian system maintains the main aspects of physiological and behavioral processes. Both circadian rhythm and sleep impact an organism's health through interaction with environmental factors. Variations in external factors influence the functionality of clock genes and disrupt 24-hour rhythmic cycle. The disrupted circadian rhythm and disregulated sleep affect an organism's health, thereby causing several disorders including cancer, depression and cardiac disorders. Considering the role of clock genes and environmental factors, extensive investigation is required focusing on pathways involved in development of life-threatening disorders. This review identifies the major risks and associated factors related with disruption in circadian system and sleep.
WOS关键词	GLUCOSE-METABOLISM IMPLICATIONS ; SLEEP-PHASE SYNDROME ; CIRCADIAN CLOCK ; SHIFT-WORK ; THERAPEUTIC IMPLICATIONS ; MOLECULAR-COMPONENTS ; LIGHT EXPOSURE ; FOOD-INTAKE ; JET-LAG ; DISORDER
WOS研究方向	Biochemistry & Molecular Biology ; Life Sciences & Biomedicine - Other Topics
语种	英语
出版者	IVYSPRING INT PUBL
WOS记录号	WOS:000433261800010
资助机构	Scientific research and service platform fund of Henan Province(2016151) ; Scientific research and service platform fund of Henan Province(2016151) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; CAS-TWAS president's fellowship ; CAS-TWAS president's fellowship ; Scientific research and service platform fund of Henan Province(2016151) ; Scientific research and service platform fund of Henan Province(2016151) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; CAS-TWAS president's fellowship ; CAS-TWAS president's fellowship ; Scientific research and service platform fund of Henan Province(2016151) ; Scientific research and service platform fund of Henan Province(2016151) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; CAS-TWAS president's fellowship ; CAS-TWAS president's fellowship ; Scientific research and service platform fund of Henan Province(2016151) ; Scientific research and service platform fund of Henan Province(2016151) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; CAS-TWAS president's fellowship ; CAS-TWAS president's fellowship
内容类型	期刊论文
源URL	[http://ir.iggcas.ac.cn/handle/132A11/88265]
专题	地质与地球物理研究所_兰州油气中心
通讯作者	Yao, Lunguang; Hou, Hongwei
作者单位	1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Hubei, Peoples R China 2.Nanyang Normal Univ, Henan Key Lab Ecol Secur Water Source Reg Mid Lin, Collaborat Innovat Ctr Water Secur Water Source R, Nanyang, Henan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Huazhong Univ Sci & Technol, Adv Biomat & Tissue Engn Ctr, Wuhan 430074, Hubei, Peoples R China 5.Huazhong Univ Sci & Technol, Dept Biomed Engn, Wuhan 430074, Hubei, Peoples R China 6.Chinese Acad Sci, Inst Geol & Geophys, Key Lab Petr Resources, Gansu Prov Key Lab Petr Resources Res, Lanzhou 730000, Gansu, Peoples R China
推荐引用方式 GB/T 7714	Khan, Suliman,Nabi, Ghulam,Yao, Lunguang,et al. Health risks associated with genetic alterations in internal clock system by external factors[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES,2018,14(7):791-798.
APA	Khan, Suliman.,Nabi, Ghulam.,Yao, Lunguang.,Siddique, Rabeea.,Sajjad, Wasim.,...&Hou, Hongwei.(2018).Health risks associated with genetic alterations in internal clock system by external factors.INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES,14(7),791-798.
MLA	Khan, Suliman,et al."Health risks associated with genetic alterations in internal clock system by external factors".INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 14.7(2018):791-798.