Decreased gyrification in major depressive disorder

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	Decreased gyrification in major depressive disorder
	Zhang, Yuanchao 1; Yu, Chunshui 3; Zhou, Yuan1,4 ; Li, Kuncheng 3; Li, Chong 1; Jiang, Tianzi 1; T. Z. Jiang
刊名	NEUROREPORT
	2009-03-04
卷号	20 期号:4 页码:378-380
关键词	complexity connectivity cortical folding local gyrification index magnetic resonance imaging major depressive disorder
ISSN号	0959-4965
文献子类	Article
英文摘要	Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder. This study investigated this issue in major depressive disorder using the local gyrification index. High-resolution magnetic resonance imaging was performed in 18 patients with first-episode major depressive disorder and 18 age-matched and sex-matched healthy individuals. The local gyrification index was applied to detect brain areas with abnormal cortical folding in major depressive disorder. Compared with healthy participants, patients with major depressive disorder showed significantly decreased local gyrification index in the bilateral mid-posterior cingulate, insula, and orbital frontal cortices, the left anterior cingulate cortex, and the right temporal operculum.; Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder. This study investigated this issue in major depressive disorder using the local gyrification index. High-resolution magnetic resonance imaging was performed in 18 patients with first-episode major depressive disorder and 18 age-matched and sex-matched healthy individuals. The local gyrification index was applied to detect brain areas with abnormal cortical folding in major depressive disorder. Compared with healthy participants, patients with major depressive disorder showed significantly decreased local gyrification index in the bilateral mid-posterior cingulate, insula, and orbital frontal cortices, the left anterior cingulate cortex, and the right temporal operculum. NeuroReport 20:378-380 (C) 2009 Wolters Kluwer Health \| Lippincott Williams & Wilkins.
学科主题	变态心理学
语种	英语
WOS记录号	WOS:000264516700006
公开日期	2011-08-22
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/5300]
专题	心理研究所_中国科学院心理研究所回溯数据库(1956-2010)
通讯作者	T. Z. Jiang
作者单位	1.Zhejiang Univ, Dept Math, Hangzhou 310027, Zhejiang, Peoples R China 2.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100190, Peoples R China 3.Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing, Peoples R China 4.Chinese Acad Sci, Inst Psychol, Ctr Social & Econ Behav, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Yuanchao,Yu, Chunshui,Zhou, Yuan,et al. Decreased gyrification in major depressive disorder[J]. NEUROREPORT,2009,20(4):378-380.
APA	Zhang, Yuanchao.,Yu, Chunshui.,Zhou, Yuan.,Li, Kuncheng.,Li, Chong.,...&T. Z. Jiang.(2009).Decreased gyrification in major depressive disorder.NEUROREPORT,20(4),378-380.
MLA	Zhang, Yuanchao,et al."Decreased gyrification in major depressive disorder".NEUROREPORT 20.4(2009):378-380.