Bifunctional Ligand Enables Efficient Gold-Catalyzed Hydroalkenylation of Propargylic Alcohol

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	Bifunctional Ligand Enables Efficient Gold-Catalyzed Hydroalkenylation of Propargylic Alcohol
	Cheng, XP; Liao, SR; Porta, A; Ma, X; Zanoni, G; Zhang, LM
刊名	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
	2018
卷号	57 期号:27 页码:8250-8254
通讯作者	gz@unipv.it ; zhang@chem.ucsb.edu
英文摘要	Using the previously designed biphenyl-2-ylphosphine ligand, featuring a remote tertiary amino group, the first gold-catalyzed intermolecular hydroalkenylation of alkynes has been developed. Synthetically valuable conjugated dienyl alcohols are formed in moderate to good yields. A range of alkenyltrifluoroborates are allowed as the alkenyl donor, and no erosion of alkene geometry and/or the propargylic configuration are detected. DFT calculations confirm the critical role of the remote basic group in the ligand as a general-base catalyst for promoting this novel gold catalysis with good efficiency.
学科主题	Chemistry
关键词[WOS]	conjugation ; gold ; ligand design ; reaction mechanisms ; synthetic methods
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/16923]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式 GB/T 7714	Cheng, XP,Liao, SR,Porta, A,et al. Bifunctional Ligand Enables Efficient Gold-Catalyzed Hydroalkenylation of Propargylic Alcohol[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2018,57(27):8250-8254.
APA	Cheng, XP,Liao, SR,Porta, A,Ma, X,Zanoni, G,&Zhang, LM.(2018).Bifunctional Ligand Enables Efficient Gold-Catalyzed Hydroalkenylation of Propargylic Alcohol.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,57(27),8250-8254.
MLA	Cheng, XP,et al."Bifunctional Ligand Enables Efficient Gold-Catalyzed Hydroalkenylation of Propargylic Alcohol".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 57.27(2018):8250-8254.