Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity

doi:10.1016/j.cej.2017.08.026

	Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity
	Huang, Lunjie 1; Zhang, Wentao 1; Chen, Kai 1; Zhu, Wenxin 1; Liu, Xinnan 1; Wang, Rong 1; Zhang, Xu 1; Hu, Na2 ; Suo, Yourui2 ; Wang, Jianlong 1
刊名	CHEMICAL ENGINEERING JOURNAL
	2017-12-15
卷号	330 页码:746-752
关键词	Biocatalysis Colorimetric Biosensor Facet Dependence Modulating Strategy Nanoceria Oxidase Mimics
DOI	10.1016/j.cej.2017.08.026
英文摘要	Nanozymes, as a robust alternative to natural enzyme, usually suffer from unsatisfactory catalytic efficiency and limited modulating flexibility. Herein, we proposed a novel strategy to conquer these disadvantages relying on the facet-selective response of external trigger molecule which boosts the oxidase-like catalysis of nanoceria. Results indicate that the trigger molecule (i.e., sulfate ion) prefers to bind to the rod-like nanoceria (on its unique {1 1 0} facets) rather than nanopolyhedra or nanocubes. Sulfate ion-treated CeO2 nanorods (SO42- /CeO2 NRs) became modulatable oxidase mimetics of high efficiency, and the catalytic efficiency (k(cat)/K-m) of SO42- /CeO2 NRs improved by nearly 20-fold (versus that of the naked CeO2 NRs) for 3,3 ',5,5 '-tetramethylbenzidine (TMB) oxidation. This modulating strategy, together with the mechanism behind, is finally applied to develop colorimetric biosensors, which paves the way for embedding the system in biological and environmental networks.
语种	英语
WOS记录号	WOS:000414083300071
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/10368]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
作者单位	1.Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Shaanxi, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Xining 810008, Qinghai, Peoples R China
推荐引用方式 GB/T 7714	Huang, Lunjie,Zhang, Wentao,Chen, Kai,et al. Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity[J]. CHEMICAL ENGINEERING JOURNAL,2017,330:746-752.
APA	Huang, Lunjie.,Zhang, Wentao.,Chen, Kai.,Zhu, Wenxin.,Liu, Xinnan.,...&Wang, Jianlong.(2017).Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity.CHEMICAL ENGINEERING JOURNAL,330,746-752.
MLA	Huang, Lunjie,et al."Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity".CHEMICAL ENGINEERING JOURNAL 330(2017):746-752.