Asymmetric Hydrogenation of Isoquinolines and Pyridines Using Hydrogen Halide Generated in Situ as Activator

	Asymmetric Hydrogenation of Isoquinolines and Pyridines Using Hydrogen Halide Generated in Situ as Activator
	Shi, Lei 2; Chen, Mu-Wang 2; Ji, Yue 2; Wang, Jie 2; Chen, Qing-An 2; Zhou, Yong-Gui 1,2
刊名	ORGANIC LETTERS
	2017-09-15
卷号	19 期号:18 页码:4988-4991
英文摘要	By employing halogenide trichloroisocyanuric acid as a traceless activation reagent, a general iridium-catalyzed asymmetric hydrogenation of isoquinolines and pyridines is developed with up to 99% ee. This method avoids tedious steps of installation and removal of the activating groups. The mechanism studies indicated that hydrogen halide generated in situ acted as an activator of isoquinolines and pyridines.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Organic
研究领域[WOS]	Chemistry
关键词[WOS]	IRIDIUM-CATALYZED HYDROGENATION ; MULTIPLE STEREOGENIC CENTERS ; HALOGEN-BOND FORMATION ; ENANTIOSELECTIVE HYDROGENATION ; DIPHOSPHINE LIGANDS ; N-BROMOSUCCINIMIDE ; SALTS ; DERIVATIVES ; COMPLEXES ; BEARING
收录类别	SCI
语种	英语
WOS记录号	WOS:000411304300072
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/150066]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Shi, Lei,Chen, Mu-Wang,Ji, Yue,et al. Asymmetric Hydrogenation of Isoquinolines and Pyridines Using Hydrogen Halide Generated in Situ as Activator[J]. ORGANIC LETTERS,2017,19(18):4988-4991.
APA	Shi, Lei,Chen, Mu-Wang,Ji, Yue,Wang, Jie,Chen, Qing-An,&Zhou, Yong-Gui.(2017).Asymmetric Hydrogenation of Isoquinolines and Pyridines Using Hydrogen Halide Generated in Situ as Activator.ORGANIC LETTERS,19(18),4988-4991.
MLA	Shi, Lei,et al."Asymmetric Hydrogenation of Isoquinolines and Pyridines Using Hydrogen Halide Generated in Situ as Activator".ORGANIC LETTERS 19.18(2017):4988-4991.