The Association of Circumcision and Prostate Cancer: A Meta-Analysis.

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	The Association of Circumcision and Prostate Cancer: A Meta-Analysis.
	Li, Yu-Dan; Teng, Yang; Dai, Yu; Ding, Hui
刊名	Asian Pacific journal of cancer prevention : APJCP
	2016
卷号	17 期号:8 页码:3823-3827
ISSN号	1513-7368
文献子类	Article
英文摘要	BACKGROUND: To investigate any association between circumcision and prostate cancer.MATERIALS AND METHODS: We searched PubMed, EMBASE, the Cochrane Library, and Chinese biomedicine literature databases up to August 2015. All case-control studies were identified which investigated associations of circumcision with prostate cancer. Three authors independently assessed study quality and extracted data. All data were analyzed using RevMan 5.3 and STATA version 11.0.RESULTS: Six case-control studies met the inclusion criteria. The pooled meta-analysis showed that there was a lower incidence of circumcision in prostate cancer patients compared with controls (OR=0.90, 95% con dence interval [CI] 0.82-0.98, P=0.01). The results of meta-analysis also showed that no significant difference was found between circumcision and less aggressive prostate cancer (OR=0.93, 95% CI 0.83-1.04, P=0.19); however, there was a lower incidence of circumcision in more aggressive prostate cancers compared with controls (OR =0.84, 95% CI 0.72-0.97, P=0.02). The Egger's results did not show any evidence of publication bias(P=0.798).CONCLUSIONS: In summary, within the limits of available data, males with circumcision appears to have a lower incidence of prostate cancer. In the future, high-quality multicenter studies are needed to thoroughly verify the outcome.
出版地	GYEONGGI-DO
语种	英语
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179321]
专题	第二临床医学院_期刊论文
推荐引用方式 GB/T 7714	Li, Yu-Dan,Teng, Yang,Dai, Yu,et al. The Association of Circumcision and Prostate Cancer: A Meta-Analysis.[J]. Asian Pacific journal of cancer prevention : APJCP,2016,17(8):3823-3827.
APA	Li, Yu-Dan,Teng, Yang,Dai, Yu,&Ding, Hui.(2016).The Association of Circumcision and Prostate Cancer: A Meta-Analysis..Asian Pacific journal of cancer prevention : APJCP,17(8),3823-3827.
MLA	Li, Yu-Dan,et al."The Association of Circumcision and Prostate Cancer: A Meta-Analysis.".Asian Pacific journal of cancer prevention : APJCP 17.8(2016):3823-3827.