An evidence-based medicine review of lymphadenectomy extent for gastric cancer | |
Yang, SH; Zhang, YC; Yang, KH; Li, YP; He, XD; Tian, JH; Lv, TH; Hui, YH; Sharma, N; Zhang, YC (reprint author), Lanzhou Univ, Hosp 2, Dept Gen Surg, 80 Cuiyingmen, Lanzhou 730030, Gansu, Peoples R China. | |
刊名 | AMERICAN JOURNAL OF SURGERY |
2009-02 | |
卷号 | 197期号:2页码:246-251 |
关键词 | Gastric neoplasm D1, D2, D3 Meta-analysis Randomized controlled trials |
ISSN号 | 0002-9610 |
DOI | 10.1016/j.amjsurg.2008.05.001 |
文献子类 | Review |
英文摘要 | BACKGROUND: Several studies in the literature have investigated the possible role of the extent of lymphadenectomy in gastric cancer treatment failure. The current study attempted to determine the effectiveness and safety of lymphadenectomy with gastrectomy for the treatment of gastric cancer. METHODS: Randomized controlled trials (RCTs) were identified by means of MEDLINE, EMBASE, Cochrane Controlled Trials Register databases, and Chinese Biomedical Database, as well as by selecting references from relevant articles. RESULTS: Overall, 14 RCTs (3,432 patients) were included in the meta-analysis. Of the D1 and D2 surgery groups, the operative mortality and postoperative morbidity were higher in the D2 group than in the D1 group, but the 3- and 5-year survival rates were not statistically different. Also the operative time was shorter in D1 compared to D2. In the D2 versus the D3 surgical group, the operative mortality, percentage of postoperative complications, operative time, and hospital stay were not significantly different. CONCLUSIONS: The results suggest that D2 and D3 surgery may not offer specific advantages for gastric cancer and instead may lead to disadvantages for patient outcomes. (C) 2009 Elsevier Inc. All rights reserved. |
学科主题 | Surgery |
出版地 | BRIDGEWATER |
语种 | 英语 |
WOS记录号 | WOS:000263454000021 |
内容类型 | 期刊论文 |
源URL | [http://ir.lzu.edu.cn/handle/262010/125995] |
专题 | 第二临床医学院_期刊论文 |
通讯作者 | Zhang, YC (reprint author), Lanzhou Univ, Hosp 2, Dept Gen Surg, 80 Cuiyingmen, Lanzhou 730030, Gansu, Peoples R China. |
推荐引用方式 GB/T 7714 | Yang, SH,Zhang, YC,Yang, KH,et al. An evidence-based medicine review of lymphadenectomy extent for gastric cancer[J]. AMERICAN JOURNAL OF SURGERY,2009,197(2):246-251. |
APA | Yang, SH.,Zhang, YC.,Yang, KH.,Li, YP.,He, XD.,...&Zhang, YC .(2009).An evidence-based medicine review of lymphadenectomy extent for gastric cancer.AMERICAN JOURNAL OF SURGERY,197(2),246-251. |
MLA | Yang, SH,et al."An evidence-based medicine review of lymphadenectomy extent for gastric cancer".AMERICAN JOURNAL OF SURGERY 197.2(2009):246-251. |
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