The prognostic role of pretreatment platelet-to-lymphocyte ratio as predictors in patients with colorectal cancer: a meta-analysis

doi:10.2217/bmm-2016-0181

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	The prognostic role of pretreatment platelet-to-lymphocyte ratio as predictors in patients with colorectal cancer: a meta-analysis
	Min, GT; Wang, YH; Yao, N; Zhao, JM; Wang, J; Wang, HP; Chen, W; Deng, SJ; Li, YM; Min, GT (reprint author), Lanzhou Univ, Hosp 1, Dept Gen Surg, Lanzhou 730000, Peoples R China.
刊名	BIOMARKERS IN MEDICINE
	2017-01
卷号	11 期号:1 页码:87-97
关键词	biomarker colorectal cancer meta-analysis platelet platelet-to-lymphocyte ratio prognosis
ISSN号	1752-0363
DOI	10.2217/bmm-2016-0181
文献子类	Article
英文摘要	Aim: This meta-analysis was designed to analyze and evaluate the prognostic role of preoperative or pretreatment platelet-to-lymphocyte ratio (PLR) in patients with colorectal cancer (CRC). Method: We searched PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Chinese Biomedical Literature Database and WanFang Database up to April 2016. Results: A total of 16 studies (n = 5068 participants) were included for this meta-analysis. Elevated PLR has a close relationship with the poor overall survival of CRC, with the pooled hazard ratio being 1.88 (95% CI: 1.50, 2.36; p < 0.00001). Conclusion: This meta-analysis indicated that pretreatment PLR may be a cost-effective and noninvasive serum biomarker for poor prognosis for patients with CRC.
学科主题	Research & Experimental Medicine
出版地	LONDON
语种	英语
WOS记录号	WOS:000393679700009
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/188638]
专题	第一临床医学院_期刊论文
通讯作者	Min, GT (reprint author), Lanzhou Univ, Hosp 1, Dept Gen Surg, Lanzhou 730000, Peoples R China.; Li, YM (reprint author), Lanzhou Univ, Hosp 2, Dept Gen Surg, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Min, GT,Wang, YH,Yao, N,et al. The prognostic role of pretreatment platelet-to-lymphocyte ratio as predictors in patients with colorectal cancer: a meta-analysis[J]. BIOMARKERS IN MEDICINE,2017,11(1):87-97.
APA	Min, GT.,Wang, YH.,Yao, N.,Zhao, JM.,Wang, J.,...&Li, YM .(2017).The prognostic role of pretreatment platelet-to-lymphocyte ratio as predictors in patients with colorectal cancer: a meta-analysis.BIOMARKERS IN MEDICINE,11(1),87-97.
MLA	Min, GT,et al."The prognostic role of pretreatment platelet-to-lymphocyte ratio as predictors in patients with colorectal cancer: a meta-analysis".BIOMARKERS IN MEDICINE 11.1(2017):87-97.