Comparison of effectiveness of right ventricular mid-septal pacing vs. apical pacing: a randomized-controlled trials

doi:10.1093/eurheartj/suw031

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	Comparison of effectiveness of right ventricular mid-septal pacing vs. apical pacing: a randomized-controlled trials
	Bai, M; Li, Q; Jiang, GX; Zhang, L; Wang, T; Zhang, Z; Zhang, Z (reprint author), Lanzhou Univ, Hosp 1, Dept Cardiol, Lanzhou 730000, Gansu, Peoples R China.
刊名	EUROPEAN HEART JOURNAL SUPPLEMENTS
	2016-05
卷号	18 期号:F 页码:F12-F18
关键词	Mid-septal pacing Apical pacing Heart function Ventricular synchrony
ISSN号	1520-765X
DOI	10.1093/eurheartj/suw031
文献子类	Article
英文摘要	The aim of the present study was to compare conventional right ventricular apical pacing (RVAP) with right ventricular mid-septal pacing (RVMSP) in terms of echocardiographic and clinical/biologic features. Ninety-six patients with high-degree atrioventricular block were randomly allocated to RVMSP (n = 50) and RVAP (n = 46). Threshold and impedance, echocardiographic left ventricular ejection fraction, ventricular dyssynchrony features, and distance during a 6-min walk test and Minnesota Living with Heart Failure Questionnaire were determined at 6 and 12 months after pacemaker implantation. Serum levels of N-terminal pro-brain natriuretic peptide were measured. At 6 months of follow-up, echocardiographic and clinical/biologic features showed no significant differences between two groups. The RVAP group had more intraventricular dyssynchrony and a trend towards a worse left ventricular ejection fraction compared with the RVMSP at 12 months of follow-up. However, no overt clinical benefits from RVMSP were found. Right ventricular mid-septal pacing was associated with decreased dyssynchrony and better left ventricular ejection fraction compared with the RVAP. Right ventricular mid-septal pacing could represent an alternative pacing site in selected patients to reduce the harmful effects of traditional RVAP.
学科主题	Cardiovascular System & Cardiology
出版地	OXFORD
资助项目	甘肃省自然科学基金计划
项目编号	Natural Science Foundation of Gansu Province [1208RJZA223]
语种	英语
WOS记录号	WOS:000377469000003
资助机构	GSSTD
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/178645]
专题	第一临床医学院_期刊论文
通讯作者	Zhang, Z (reprint author), Lanzhou Univ, Hosp 1, Dept Cardiol, Lanzhou 730000, Gansu, Peoples R China.
推荐引用方式 GB/T 7714	Bai, M,Li, Q,Jiang, GX,et al. Comparison of effectiveness of right ventricular mid-septal pacing vs. apical pacing: a randomized-controlled trials[J]. EUROPEAN HEART JOURNAL SUPPLEMENTS,2016,18(F):F12-F18.
APA	Bai, M.,Li, Q.,Jiang, GX.,Zhang, L.,Wang, T.,...&Zhang, Z .(2016).Comparison of effectiveness of right ventricular mid-septal pacing vs. apical pacing: a randomized-controlled trials.EUROPEAN HEART JOURNAL SUPPLEMENTS,18(F),F12-F18.
MLA	Bai, M,et al."Comparison of effectiveness of right ventricular mid-septal pacing vs. apical pacing: a randomized-controlled trials".EUROPEAN HEART JOURNAL SUPPLEMENTS 18.F(2016):F12-F18.